汎 마우스 植物凝集素로 分類된 사람 血淸型에 關한 硏究 = A Study on the Human Serum Types Classified by the Pan-mouse Phytagglutinins

다국어 초록 (Multilingual Abstract)

Since the introduction of phytagglutinin(PHA) by Stillmark in 1888, there have been a lot of research works on PHA by many investigators.
Recently the utilization of PHA in the medical or medicolegal field is increaing, especially as a lectin for the blood grouping, as a mitogen for the artificial culture of human cells and as a determinant of the receptor specificity of various tumor cells.
In this study were carried out agglutination tests of mouse red blood cells by three PHAs -A. plantago L., T. kirilowii Max. and C. Chamlagu Lam. -and by 1353 human sera And human sera were also examined whether or not they inhibit the agglutination activities of the three PHAs with the mouse red blood cells.
The results could be summarized as follows.
1. Any of the PHAs could agglutinate mouse red blood cells, so the PHAs are called pan-mouse PHAs.
2. The human sera were classified into two types by their agglutination activities to mouse red blood cells.
3 The human sera were also classified into two types by their agglutination inhibition properties to pan·mouse PHAs.
4. Statistically it was demonstrated that there is a close relationship between the serum types classified by agglutination activities to mouse red blood cells and the serum types classified by agglutination inhibition properties to pan-mouse PHAs.
5. It was also demonstrated that the agglutination substance to mouse red blood cells and agglutination inhibition substance to pan-mouse PHAs in human sera are quite different each other and exist independently.
6. This experimental study suggested that agglutination inhibition substance to pan-mouse PHAs exists in all human sera and the classification of serum types by agglutionation inhibition properties to pan-mouse PHAs is influenced by existence of agglutionation substance to mouse red blood cells in human sera.