유방외 Paget병의 임상적 연구 = Clinical Study of Extramammary Paget`s Disease

다국어 초록 (Multilingual Abstract)

Background: Extramammary Paget's disease (EMPD) is a rare skin neoplasm usually observed in apocrine-bearing regions. There were no comprehensive studies about the clinical features of EMPD in Korea. Objeetive: Our purpose was to study in detail the clinical findings of EMPD. Methods: The fifteen patients with EMPD at our institution over ten years were retrieved. Clinical records and pathology slides of the patients were reviewed retrospectively. Results: l. EMPD was seen more frequently in men than women (14:1 male:female ratio). 2. The most predilection site was penoscrotal area. 3. Thirteen percent of patients (2/15) with the disease had an associated underlying malignancy. 4. Twenty-two percent (2/9) of patients with wide excision had local recurrence during the follow-up period. Conclusion: EMPD in Korea may be characterized by male predominance and penoscrotal location. The incidence of concomitant malignancy may be lower than that in Caucasian. However, a search for internal malignancy and regular follow-up is still warranted.