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      고콜레스테롤식이와 솔잎분말 첨가식이 섭취 시 수영운동이 혈중 콜레스테롤 및 염증성 사이토카인에 미치는 영향 = The effect of high-cholesterol diet and pine needle powerd-added intake swimming exercise on blood profile and inflammatory cytokine in rats

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      https://www.riss.kr/link?id=A106946664

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      다국어 초록 (Multilingual Abstract) kakao i 다국어 번역

      The purpose of this study is to examine how a pine needle powder-added diet and swimming exercise influence blood profile and inflammatory cytokine in a high cholesterol diet. 42 male Sprague-Dawley rats were made to practice a pine needle powder-added diet and swimming exercise along with a high cholesterol diet for six weeks. Concerning the results of blood lipids, the TG content was significantly low in the HCPNE, and LDL-C was significantly high in the EX compared with the CON and EX and HDL-C was s tatistically s ignificantly high in the EX. According to the results of TNF-α concentration in the change of inflammatory cytokine, the HC, HCE, and HCPN indicated significantly higher concentration than the CON and EX, and according to the results of NFκB concentration, no significant difference was found. According to the results of IL-6 concentration, compared with the CON, the EX and HCPNE were found to be significantly low. herefore, according to the results of this study, the exercise and pine needle powder-added diet activated AMPK and the acceleration of blood profile as the result of the, and this led to the decrease of fat synthesis. Moreover, regarding the results of pine needle powder intake in the diet, pharmacological compounds contained in pine needles such as phenols and flavonoids are thought to influence blood profile, anti-inflammatory positively. This author deems that the results of this study provide foundational material regarding the influence of exercise and pine needle powder-added diet’s complex treatment on anti-obesity improvements.
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      The purpose of this study is to examine how a pine needle powder-added diet and swimming exercise influence blood profile and inflammatory cytokine in a high cholesterol diet. 42 male Sprague-Dawley rats were made to practice a pine needle powder-adde...

      The purpose of this study is to examine how a pine needle powder-added diet and swimming exercise influence blood profile and inflammatory cytokine in a high cholesterol diet. 42 male Sprague-Dawley rats were made to practice a pine needle powder-added diet and swimming exercise along with a high cholesterol diet for six weeks. Concerning the results of blood lipids, the TG content was significantly low in the HCPNE, and LDL-C was significantly high in the EX compared with the CON and EX and HDL-C was s tatistically s ignificantly high in the EX. According to the results of TNF-α concentration in the change of inflammatory cytokine, the HC, HCE, and HCPN indicated significantly higher concentration than the CON and EX, and according to the results of NFκB concentration, no significant difference was found. According to the results of IL-6 concentration, compared with the CON, the EX and HCPNE were found to be significantly low. herefore, according to the results of this study, the exercise and pine needle powder-added diet activated AMPK and the acceleration of blood profile as the result of the, and this led to the decrease of fat synthesis. Moreover, regarding the results of pine needle powder intake in the diet, pharmacological compounds contained in pine needles such as phenols and flavonoids are thought to influence blood profile, anti-inflammatory positively. This author deems that the results of this study provide foundational material regarding the influence of exercise and pine needle powder-added diet’s complex treatment on anti-obesity improvements.

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      참고문헌 (Reference)

      1 이경선, "와송추출물의 비만유발 ICR 마우스에서의 항비만 효과" 한국미생물·생명공학회 45 (45): 284-290, 2017

      2 최희정, "솔잎추출액을 이용한 Microcystis aeruginosa 제거 연구" 한국물환경학회 33 (33): 8-14, 2017

      3 홍택근, "솔잎의 기능성과 식품에 대한 응용" 34 (34): 48-52, 2001

      4 이은, "솔잎분말이 과산화지질을 급여한 흰쥐의 혈장 및 간장의 지질구성과 항산화능에 미치는 영향" 한국식품영양과학회 32 (32): 926-930, 2003

      5 전정례, "솔잎, 홍차 및 녹차 추출물 함유 조성물의 항비만 효과" 한국응용생명화학회 48 (48): 375-381, 2005

      6 이윤형, "솔잎(Pinus strobus)추출물을 함유한 건강식품의 개발" 25 (25): 379-383, 1996

      7 민희정, "소나무 단리 화합물의 항산화 및 Glucokinase 활성 평가" 2019 (2019): 92-92, 2019

      8 박미영, "발아현미가 LPS로 유도된 지방세포의 염증반응에 미치는 영향" 한국식생활문화학회 33 (33): 337-344, 2018

      9 Mokhtarzade, M., "Weight control and physical exercise in people with multiple sclerosis : Current knowledge and future perspectives" 43 : 240-246, 2019

      10 Bradley, R. L., "Voluntary exercise improves insulin sensitivity and adipose tissue inflammation in diet-induced obese mice" 295 (295): E586-E594, 2008

      1 이경선, "와송추출물의 비만유발 ICR 마우스에서의 항비만 효과" 한국미생물·생명공학회 45 (45): 284-290, 2017

      2 최희정, "솔잎추출액을 이용한 Microcystis aeruginosa 제거 연구" 한국물환경학회 33 (33): 8-14, 2017

      3 홍택근, "솔잎의 기능성과 식품에 대한 응용" 34 (34): 48-52, 2001

      4 이은, "솔잎분말이 과산화지질을 급여한 흰쥐의 혈장 및 간장의 지질구성과 항산화능에 미치는 영향" 한국식품영양과학회 32 (32): 926-930, 2003

      5 전정례, "솔잎, 홍차 및 녹차 추출물 함유 조성물의 항비만 효과" 한국응용생명화학회 48 (48): 375-381, 2005

      6 이윤형, "솔잎(Pinus strobus)추출물을 함유한 건강식품의 개발" 25 (25): 379-383, 1996

      7 민희정, "소나무 단리 화합물의 항산화 및 Glucokinase 활성 평가" 2019 (2019): 92-92, 2019

      8 박미영, "발아현미가 LPS로 유도된 지방세포의 염증반응에 미치는 영향" 한국식생활문화학회 33 (33): 337-344, 2018

      9 Mokhtarzade, M., "Weight control and physical exercise in people with multiple sclerosis : Current knowledge and future perspectives" 43 : 240-246, 2019

      10 Bradley, R. L., "Voluntary exercise improves insulin sensitivity and adipose tissue inflammation in diet-induced obese mice" 295 (295): E586-E594, 2008

      11 Erdal, M., "The role of HMGB1 in liver inflammation in obese rats" 27 : 1-10, 2019

      12 Venkatesan, T., "Pinus densiflora needle supercritical fluid extract suppresses the expression of pro-inflammatory mediators iNOS, IL-6 and IL-1β, and activation of inflammatory STAT1 and STAT3 signaling proteins in bacterial lipopolysaccharidechallenged murine macrophages" 25 (25): 18-, 2017

      13 Shityakov, S., "Phytochemical and pharmacological attributes of piperine : A bioactive ingredient of black pepper" 176 : 149-161, 2019

      14 박재희, "Optimization of Mixing Ratio to Improve Antioxidant Activity of Aged Garlic with Pine Needle Using Response Surface Methodology" 한국식품영양과학회 22 (22): 241-245, 2017

      15 Wang, Y. H., "Niemann-Pick Type C2 Protein Regulates Free Cholesterol Accumulation and Influences Hepatic Stellate Cell Proliferation and Mitochondrial Respiration Function" 19 (19): 1678-, 2018

      16 Ahn, S., "Gold nanoparticles synthesized using Panax ginseng leaves suppress inflammatory -mediators production via blockade of NF-κB activation in macrophages" 45 (45): 270-276, 2017

      17 Wang, H., "Ginseng leaf-stem : bioactive constituents and pharmacological functions" 22 (22): 20-, 2009

      18 Kim, J. K., "Gingerol prevents UVB-induced ROS production and COX-2 expression in vitro and in vivo" 41 (41): 603-614, 2007

      19 Ren, P., "Frankincense, pine needle and geranium essential oils suppress tumor progression through the regulation of the AMPK/mTOR pathway in breast cancer" 39 (39): 129-137, 2018

      20 Singh, L., "Ethnobotany and Pharmacology of Pinus Species Growing Naturally in Indian Himalayas : A Plant Review" 20 (20): 1281-1287, 2019

      21 Friedewald, W. T., "Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge" 18 (18): 499-502, 1972

      22 Al-Muzafar, H. M., "Efficacy of functional foods mixture in improving hypercholesterolemia, inflammatory and endothelial dysfunction biomarkers-induced by high cholesterol diet" 16 (16): 194-, 2017

      23 Kim, K. W., "Effect of modified fasting therapy on body weight, fat and muscle mass, and blood chemistry in patients with obesity" 36 (36): 57-62, 2016

      24 Yang, Y., "Effect of aerobic exercise and ginsenosides on lipid metabolism in diet-induced hyperlipidemia mice" 20 (20): 563-, 1999

      25 Novák, S., "Determination of the inhibitory effect of a biologically active preparation on the reproduction of micro-organisms from the intestines of ruminants" 32 (32): 337-342, 1987

      26 Yadav, R., "Consumption of probiotic Lactobacillus fermentum MTCC : 5898-fermented milk attenuates dyslipidemia, oxidative stress, and inflammation in male rats fed on cholesterol-enriched diet" 11 (11): 509-518, 2019

      27 Kim, M., "Capillarisin attenuates exercise-induced muscle damage through MAPK and NF-κB signaling" 32 : 30-36, 2017

      28 Huang, Y., "Cannabidiol protects livers against nonalcoholic steatohepatitis induced by high-fat high cholesterol diet via regulating NFκB and NLRP3 inflammasome pathway" 234 (234): 21224-21234, 2019

      29 Liu, R., "Anti-Obesity effects of protopanaxdiol types of Ginsenosides isolated from the leaves of American ginseng(Panax quinquefolius L. )in mice fed with a high-fat diet" 81 (81): 1079-1087, 2010

      30 Hardie, D. G., "AMP-activated/SNF1 protein kinases : conserved guardians of cellular energy" 8 (8): 774-785, 2007

      31 서미혜, "2018 Korean Society for the Study of Obesity Guideline for the Management of Obesity in Korea" 대한비만학회 28 (28): 40-45, 2019

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      2026 평가예정 재인증평가 신청대상 (재인증)
      2020-01-01 평가 등재학술지 유지 (재인증) KCI등재
      2017-01-01 평가 등재학술지 유지 (계속평가) KCI등재
      2013-01-01 평가 등재학술지 유지 (등재유지) KCI등재
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      2009-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2008-01-01 평가 신청제한 (등재후보1차) KCI등재후보
      2007-01-01 평가 등재후보 1차 FAIL (등재후보1차) KCI등재후보
      2006-01-01 평가 등재후보학술지 유지 (등재후보2차) KCI등재후보
      2005-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2004-01-01 평가 등재후보 1차 FAIL (등재후보1차) KCI등재후보
      2003-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.66 0.66 0.67
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.66 0.66 0.593 0.18
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