단안 망막정맥폐쇄 환자의 무증상 반대안의 사상판 두께

다국어 초록 (Multilingual Abstract)

Purpose: To compare the lamina cribrosa thickness in fellow eyes of patients with unilateral retinal vein occlusion (RVO) with the normal control eyes and the type of RVO.
Methods: This study included 40 patients with unilateral RVO and 45 normal control subjects. We compared the lamina cribrosa thickness between the RVO eyes and the fellow eyes, the fellow eyes and the normal control eyes and the type of RVO eyes. We measured central lamina thickness using enhanced depth imaging spectral-domain optical coherence tomography.
Results: In patients with unilateral RVO, central lamina cribrosa thickness was not significantly different between the RVO eyes (211.33 μm) and the fellow eyes (204.13 μm; p = 0.202). However, central lamina cribrosa thickness in the fellow eyes was sig-nificantly reduced compared with the normal control eyes (217.76 μm; p = 0.046). Central lamina cribrosa thickness in the fellow eyes according to the type of RVO was not statistically significantly different (p = 0.672). Conclusions: This study showed that the central lamina cribrosa thickness in the fellow eyes of patients with unilateral RVO was thinner than in normal patients. Therefore, the lamina cribrosa thickness may be associated with RVO as well as glaucoma.

참고문헌 (Reference)

1 백동원, "스펙트럼 영역 빛간섭단층촬영으로 측정한 사상판 두께의 연령에 따른 변화" 대한안과학회 54 (54): 1261-1268, 2013

2 윤삼영, "단안 망막정맥폐쇄가 있는 환자의 반대쪽 안의 녹내장성 손상에 대한 고찰" 대한안과학회 50 (50): 120-127, 2009

3 Lee EJ., "Visualization of the lamina cribrosa using enhanced depth imaging spectral-domain optical coherence tomography" 152 : 87-95.e1, 2011

4 Bonomi L., "Vascular risk factors for primary open angle glaucoma : the Egna-Neumarkt Study" 107 : 1287-1293, 2000

5 Quigley HA., "The histology of human glaucoma cupping and optic nerve damage : clinicopathologic correlation in 21 eyes" 86 : 1803-1830, 1979

6 Mi XS., "The current research status of normal tension glaucoma" 9 : 1563-1571, 2014

7 Johnston RL., "Risk factors of branch retinal vein occlusion" 103 : 1831-1832, 1985

8 Sperduto RD., "Risk factors for hemiretinal vein occlusion : comparison with risk factors for central and branch retinal vein occlusion : the eye disease case-control study" 105 : 765-771, 1998

9 "Risk factors for central retinal vein occlusion. The Eye Disease Case-Control Study Group" 114 : 545-554, 1996

10 Kondo Y., "Retrobulbar hemodynamics in normal-tension glaucoma with asymmetric visual field change and asymmetric ocular perfusion pressure" 130 : 454-460, 2000

11 Soni KG., "Retinal vascular occlusion as a presenting feature of glaucoma simplex" 55 : 192-195, 1971

12 Luntz MH., "Retinal vascular accidents in glaucoma and ocular hypertension" 25 : 163-167, 1980

13 Kim MJ., "Retinal nerve fiber layer thickness is decreased in the fellow eyes of patients with unilateral retinal vein occlusion" 118 : 706-710, 2011

14 Pasquale LR., "Prospective study of type 2 diabetes mellitus and risk of primary open-angle glaucoma in women" 113 : 1081-1086, 2006

15 Burgoyne CF., "Premise and prediction-how optic nerve head biomechanics underlies the susceptibility and clinical behavior of the aged optic nerve head" 17 : 318-328, 2008

16 Minckler DS., "Orthograde and retrograde axoplasmic transport during acute ocular hypertension in the monkey" 16 : 426-441, 1977

17 Quigley HA., "Optic nerve damage in human glaucoma. II. The site of injury and susceptibility to damage" 99 : 635-649, 1981

18 Jonas JB., "Lamina cribrosa thickness and spatial relationships between intraocular space and cerebrospinal fluid space in highly myopic eyes" 45 : 2660-2665, 2004

19 Ren R., "Lamina cribrosa and peripapillary sclera histomorphometry in normal and advanced glaucomatous Chinese eyes with various axial length" 50 : 2175-2184, 2009

20 Frucht J., "Intraocular pressure in retinal vein occlusion" 68 : 26-28, 1984

21 Hayreh SS., "Intraocular pressure abnormalities associated with central and hemicentral retinal vein occlusion" 111 : 133-141, 2004

22 Kim SJ., "Four cases of normal-tension glaucoma with disk hemorrhage combined with branch retinal vein occlusion in the contralateral eye" 137 : 357-359, 2004

23 Sigal IA., "Finite element modeling of optic nerve head biomechanics" 45 : 4378-4387, 2004

24 Park SC., "Enhanced depth imaging optical coherence tomography of deep optic nerve complex structures in glaucoma" 119 : 3-9, 2012

25 Park HY., "Enhanced depth imaging detects lamina cribrosa thickness differences in normal tension glaucoma and primary open-angle glaucoma" 119 : 10-20, 2012

26 Levy NS., "Displacement of optic nerve head in response to short-term intraocular pressure elevation in human eyes" 102 : 782-786, 1984

27 Young Cheol Yoo, "Disc Hemorrhages in Patients with both Normal Tension Glaucoma and Branch Retinal Vein Occlusion in Different Eyes" 대한안과학회 21 (21): 222-227, 2007

28 Bellezza AJ., "Deformation of the lamina cribrosa and anterior scleral canal wall in early experimental glaucoma" 44 : 623-637, 2003

29 Beaumont PE., "Cup-to-disc ratio, intraocular pressure, and primary open-angle glaucoma in retinal venous occlusion" 109 : 282-286, 2002

30 김소아, "Comparison between Glaucomatous and Non-glaucomatous Eyes with Unilateral Retinal Vein Occlusion in the Fellow Eye" 대한안과학회 27 (27): 440-445, 2013

31 Beaumont PE., "Clinical characteristics of retinal venous occlusions occurring at different sites" 86 : 572-580, 2002

32 Simons BD., "Branch retinal vein occlusion. Axial length and other risk factors" 17 : 191-195, 1997

33 Sigal IA., "Biomechanics of the optic nerve head" 88 : 799-807, 2009

34 Gaasterland D., "Axoplasmic flow during chronic experimental glaucoma. 1. Light and electron microscopic studies of the monkey optic nervehead during development of glaucomatous cupping" 17 : 838-846, 1978

35 Radius RL., "Anatomy of the optic nerve head and glaucomatous optic neuropathy" 32 : 35-44, 1987

36 Jonas JB., "Anatomic relationship between lamina cribrosa, intraocular space, and cerebrospinal fluid space" 44 : 5189-5195, 2003

37 Albon J., "Age related compliance of the lamina cribrosa in human eyes" 84 : 318-323, 2000

38 Yang H., "3-D histomorphometry of the normal and early glaucomatous monkey optic nerve head : lamina cribrosa and peripapillary scleral position and thickness" 48 : 4597-4607, 2007