The effect of naloxone on blood flow was studied in cats subjected to 400 gm-㎝ contusion injuries of the thoracic spinal cord. Ten cats were treated with 10㎎/㎏ naloxone 45 to 60 minutes after injury. Ten cats were given 10㎖ of saline instead o...
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https://www.riss.kr/link?id=A40035817
1988
Korean
510
SCOPUS,SCIE,KCI등재
학술저널
887-895(9쪽)
0
상세조회0
다운로드다국어 초록 (Multilingual Abstract)
The effect of naloxone on blood flow was studied in cats subjected to 400 gm-㎝ contusion injuries of the thoracic spinal cord. Ten cats were treated with 10㎎/㎏ naloxone 45 to 60 minutes after injury. Ten cats were given 10㎖ of saline instead o...
The effect of naloxone on blood flow was studied in cats subjected to 400 gm-㎝ contusion injuries of the thoracic spinal cord. Ten cats were treated with 10㎎/㎏ naloxone 45 to 60 minutes after injury. Ten cats were given 10㎖ of saline instead of naloxone, and 10 cats were neither injured nor treated. Hydrogen clearance was used to measure blood flow in the lateral white column at the contusion site.
Naloxone, given intravenously, significantly improved the blood flow rates in the lateral column white matter. At 2 hours after injury, the mean blood flow in the saline-treated cats fell to 6.01±0.90㎖/100gm/min, whereas it increased 8.47±1.14㎖/100gm/min in naloxone-treated cats(p<0.05). The authors conclude that naloxone may be useful for spinal cord injury.
실험적 뇌지주막하 출혈에 의한 뇌혈관 연축에 대한 Vasodilators의 영향
허혈성 뇌혈관 질환환자의 국소뇌혈류와 그 임상적용에 관한 연구