난소절제 암컷 비만 쥐에서 지방대사와 열 발생 관련 유전자 조절에 대한 수영운동의 영향 = Effects of Swimming Exercise on the Regulation of Fat Metabolism and Thermogenesis-Related Genes in Ovariectimized Female Obese Mice

다국어 초록 (Multilingual Abstract)

This study investigated the regulation mechanism of swimming exercise on obesity by investigating the expression of genes related to fat metabolism and heat generation in adipose tissue, liver and muscle tissue of ovariectomized female mice fed a high fat diet. In OVX/Ex compared to OVX, body weight gain was blunted. The expression of lipogenesis genes in adipose tissue, liver and muscle tissue was decreased in OVX/Ex compared to OVX.
However, the expression of lipolysis gene in adipose tissue, liver and muscle tissue was increased in OVX/Ex compared to OVX. In addition, in adipose tissue, liver and muscle tissue, the expression of the UCPs genes related to thermogenesis was increased in OVX/Ex compared to OVX. Therefore, this study suggested that swimming exercise positively regulates fat metabolism and thermogenesis in adipose tissue, liver and muscle tissue for obesity control in ovariectomized female mice fed a high fat diet, an animal model of postmenopausal obese women.