위암환자에서 수술전 Polyadenylic-Polyuridylic Acid 투여가 말초혈액과 영역림프절 단핵구의 NK 및 LAK 활성도에 미치는 영향 = Effect of Preoperative Administration of Polyadenylic-polyuridylic Acid on NK and LAK Activities of Mononuclear Cell of Peripheral Blood and Regional Lymphnode from Patients with Gastric Carcinoma

다국어 초록 (Multilingual Abstract)

Although the biological significance of the regional lymphnode as a barrier to tumor remains unclear, the clinical prognostic relevance of the neoplastic infiltration of these nodes is accepted. The most potent antitumor effector cells may be expected to be present within or around the site of tumor growth. However, lymphocytes isolated from solid tumor, cancer ascites fluid, and carcinomatous pleural effusion have been shown to expresse low natural killer (NK) activity or none at all. Similarly, it has been reported that lymphnode can be regarded as an NK-deficient tissue, since more limited cytotoxic activity is recorded in the lymphnode cells. (continue...)