조현병 환자에서 자살 시도 및 폭력성과 임상 증상과의 관련성 = Association of Suicidal Attempts and Violence With Clinical Symptoms in Schizophrenia

다국어 초록 (Multilingual Abstract)

Objective : To evaluate the association between suicidality with violent hostility and psychopathology in schizophrenia.
Methods : Seventy nine schizophrenic patients were interviewed and evaluated regarding their psychopathology with Positive and Negative Symptom Scale (PANSS). Suicidal attempt number, suicidality (ideation, plan or attempts), and hostility with violent acts in patients were also investigated.
Results : In schizophrenic patients, suicidal attempts were significantly correlated with positive symptoms (r=0.336, p=0.002) and general symptoms (r=0.26, p=0.021). Their suicidality was also significantly correlated with all psychopathology (p=0.000). In addition, their hostility was associated with psychopathology, especially in those with positive symptoms (r=0.29, p=0.01).
Conclusion : Suicidal attempts and violent behaviors showed association with psychopathology in schizophrenia. This suggests that symptoms of schizophrenia need to be treated as early as possible. (Anxiety and Mood 2024;20(2):49-53)

참고문헌 (Reference)

1 Large MM, "Violence in first-episode psychosis : a systematic review and meta-analysis" 125 : 209-220, 2011

2 Keck PE, Jr, "The efficacy of atypical antipsychotics in the treatment of depressive symptoms, hostility, and suicidality in patients with schizophrenia" 61 (61): 4-9, 2000

3 Harris EC, "Suicide as an outcome for mental disorders. A meta-analysis" 170 : 205-228, 1997

4 Radomsky ED, "Suicidal behavior in patients with schizophrenia and other psychotic disorders" 156 : 1590-1595, 1999

5 Mahler MS, "Some preliminary notes on the development of basic moods, including depression" 11 (11): 250-258, 1966

6 Allebeck P, "Schizophrenia : a life-shortening disease" 15 : 81-89, 1989

7 Bo S, "Risk factors for violence among patients with schizophrenia" 31 : 711-726, 2011

8 Nielssen O, "Rates of homicide during the first episode of psychosis and after treatment : a systematic review and meta-analysis" 36 : 702-712, 2010

9 Ritsner M, "Quality of life and coping with schizophrenia symptoms" 12 : 1-9, 2003

10 Koivumaa-Honkanen H, "Life satisfaction and suicide : a 20-year follow-up study" 158 : 433-439, 2001

11 Ponizovsky AM, "Life satisfaction and suicidal attempts among persons with schizophrenia" 44 : 442-447, 2003

12 Larsen TK, "Early detection and intervention in first-episode schizophrenia : a critical review" 103 : 323-334, 2001

13 Altamura AC, "Duration of untreated psychosis as a predictor of outcome in first-episode schizophrenia : a retrospective study" 52 : 29-36, 2001

14 Ferracuti S, "Correlations between cortical gyrification and schizophrenia symptoms with and without comorbid hostility symptoms" 13 : 1092784-, 2022

15 Altamura AC, "Clinical variables related to suicide attempts in schizophrenic patients : a retrospective study" 60 : 47-55, 2003

16 Breier A, "Characterization of schizophrenic patients who commit suicide" 141 : 206-209, 1984

17 Bartels SJ, "Characteristic hostility in schizophrenic outpatients" 17 : 163-171, 1991

18 Laursen TM, "Cause-specific life years lost among persons diagnosed with schizophrenia : Is it getting better or worse?" 206 : 284-290, 2019

19 Keers R, "Association of violence with emergence of persecutory delusions in untreated schizophrenia" 171 : 332-339, 2014

20 Jovanovic N, "Association between psychopathology and suicidal behavior in schizophrenia. A cross-sectional study of 509 participants" 34 : 374-381, 2013