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      운동 형태가 다른 달리기 시 혈중 항염증 사이토카인 변화 = Alteration of Plasma Anti-inflammatory Cytokines during Different Types of Running Exercise

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      https://www.riss.kr/link?id=A76509216

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      다국어 초록 (Multilingual Abstract)

      The purpose of this study was to investigate the alteration of plasma anti-inflammatory cytokines, including interleukin-6 (IL-6), soluble TNF receptor (sTNFr), IL-10, and interleukin-1 receptor antagonist (IL-1ra), during different types of running e...

      The purpose of this study was to investigate the alteration of plasma anti-inflammatory cytokines, including interleukin-6 (IL-6), soluble TNF receptor (sTNFr), IL-10, and interleukin-1 receptor antagonist (IL-1ra), during different types of running exercise(level and downhill running). Seven healthy male college students completed two different exercise trials on separate occasions: (1) level treadmill running at 75% VO₂max for 30 min; (2) downhill treadmill running (?12% gradient) at 75% VO₂max for 30 min. Blood was sampled before, immediately after, and 1 h, 4 h, 24 h after exercise. Visual analog scale (VAS) score was obtained at the same time point. Plasma was analyzed for cytokines and creatine kinase (CK) activity. The plasma concentrations of IL-6 increased significantly (P<0.05) after exercise in both trials but there was a difference in pattern of change between trials. CK activity and VAS score increased significantly after the downhill running but not in level running trial. IL-10, as like IL-6, increased significantly (P<0.05 or P<0.01) after downhill running but not in level running. There was no significant alteration of sTNFr and IL-1ra in both running trials. In conclusion, there was a different pattern in response of exercise-induced anti-inflammatory cytokines such as IL-6 and IL-10 between running types (level and downhill).

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      목차 (Table of Contents)

      • Abstract
      • 1. 서론
      • 2. 연구 방법
      • 3. 결과
      • 4. 논의
      • Abstract
      • 1. 서론
      • 2. 연구 방법
      • 3. 결과
      • 4. 논의
      • 5. 결론
      • 후기
      • 인용문헌
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      참고문헌 (Reference)

      1 Dinarello,C.A., "The role of the interleukin-1-receptor antagonist in blocking inflammation mediated by interleukin-1" 343 (343): 732-734, 2000

      2 Petersen,A.M., "The antiinflammatory effect of exercise" 98 (98): 154-1162, 2005

      3 Pedersen,B.K., "Searching for the exercise factor: is IL-6 a candidate?" 24 (24): 113-119, 2003

      4 Ostrowski,K., "Pro- and anti-inflammatory cytokine balance in strenuous exercise in humans" 515 (515): 287-291, 1999

      5 Peake,J.M., "Plasma cytokine changes in relation to exercise intensity and muscle damage" 95 (95): 514-521, 2005

      6 Elenkov,I.J., "Neuroendocrine regulation of IL-12 and TNF-alpha/IL-10 balance. Clinical implications" 917 : 94-105, 2000

      7 Toft,A.D., "N-3 polyunsaturated fatty acids do not affect cytokine response to strenuous exercise" 89 (89): 2401-2406, 2000

      8 Febbraio,M.A., "Musclederived interleukin-6: mechanisms for activation and possible biological roles" 16 (16): 1335-1347, 2002

      9 Pedersen,B.K., "Muscle-derived interleukin-6: possible biological effects" 536 (536): 329-337, 2001

      10 Jonsdottir,I.H., "Muscle contractions induce interleukin-6 mRNA production in rat skeletal muscles" 528 (528): 57-163, 2000

      1 Dinarello,C.A., "The role of the interleukin-1-receptor antagonist in blocking inflammation mediated by interleukin-1" 343 (343): 732-734, 2000

      2 Petersen,A.M., "The antiinflammatory effect of exercise" 98 (98): 154-1162, 2005

      3 Pedersen,B.K., "Searching for the exercise factor: is IL-6 a candidate?" 24 (24): 113-119, 2003

      4 Ostrowski,K., "Pro- and anti-inflammatory cytokine balance in strenuous exercise in humans" 515 (515): 287-291, 1999

      5 Peake,J.M., "Plasma cytokine changes in relation to exercise intensity and muscle damage" 95 (95): 514-521, 2005

      6 Elenkov,I.J., "Neuroendocrine regulation of IL-12 and TNF-alpha/IL-10 balance. Clinical implications" 917 : 94-105, 2000

      7 Toft,A.D., "N-3 polyunsaturated fatty acids do not affect cytokine response to strenuous exercise" 89 (89): 2401-2406, 2000

      8 Febbraio,M.A., "Musclederived interleukin-6: mechanisms for activation and possible biological roles" 16 (16): 1335-1347, 2002

      9 Pedersen,B.K., "Muscle-derived interleukin-6: possible biological effects" 536 (536): 329-337, 2001

      10 Jonsdottir,I.H., "Muscle contractions induce interleukin-6 mRNA production in rat skeletal muscles" 528 (528): 57-163, 2000

      11 Lieber,R.L., "Morphologic and mechanical basis of delayed-onset muscle soreness" 10 (10): 67-73, 2002

      12 Evans,W.J., "Metabolic changes following eccentric exercise in trained and untrained men" 61 (61): 1864-1868, 1986

      13 Steensberg, A, "Interleukin-6 production in contracting human skeletal muscle is influenced by pre-exercise muscle glycogen content" 537 (537): 633-639, 2001

      14 Akira,S., "Interleukin-6 in biology and medicine" 54 : 1-78, 1993

      15 Fischer,C.P., "Interleukin-6 in acute exercise and training: what is the biological relevance? Exerc" 12 : 6-33, 2006

      16 Tilg,H., "Interleukin-6 (IL-6) as an antiinflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55" 83 (83): 113-118, 1994

      17 Pretolani,M., "Interleukin-10: an anti-inflammatory cytokine with therapeutic potential" 29 (29): 1164-1171, 1999

      18 Moore,K.W., "Interleukin-10" 11 : 165-190, 1993

      19 Dinarello,C.A., "Interleukin-1 and tumor necrosis factor: effector cytokines in autoimmune diseases" 4 (4): 133-145, 1992

      20 Gabay,C., "Interleukin 1 receptor antagonist (IL-1Ra) is an acute-phase protein" 99 (99): 2930-2940, 1997

      21 Brenner,I.K., "Impact of three different types of exercise on components of the inflammatory response" 80 (80): 452-460, 1999

      22 Nieman,D.C., "Immune response to heavy exertion" 82 (82): 1385-1394, 1997

      23 Tilg,H., "IL-6 and APPs: anti-inflammatory and immunosuppressive mediators" 18 (18): 428-432, 1997

      24 Clarkson,P.M., "Exerciseinduced muscle damage in humans" 81 (81): S52-69, 2002

      25 Ebbeling,C.B., "Exerciseinduced muscle damage and adaptation" 7 (7): 207-234, 1989

      26 Bruunsgaard,H., "Exercise-induced increase in serum interleukin-6 in humans is related to muscle damage" 499 (499): 833-841, 1997

      27 Tall,A.R., "Exercise to reduce cardiovascular risk-how much is enough?" 47 (47): 1522-1524, 2002

      28 Moldoveanu,A.I., "Exercise elevates plasma levels but not gene expression of IL-1βeta, IL-6, and TNF-alpha in blood mononuclear cells" 89 (89): 1499-1504, 2000

      29 Pedersen,B.K., "Exercise and the immune system: regulation, integration, and adaptation" 80 (80): 1055-1081, 2000

      30 Ostrowski,K., "Evidence that interleukin-6 is produced in human skeletal muscle during prolonged running" 508 (508): 949-953, 1998

      31 Croisier,J.L., "Effects of training on exercise-induced muscle damage and interleukin 6 production" 22 (22): 208-212, 1999

      32 Milias,G.A., "Effects of eccentric exercise-induced muscle injury on blood levels of platelet activating factor (PAF) and other inflammatory markers" 95 (95): 504-513, 2005

      33 Toft,A.D., "Cytokine response to eccentric exercise in young and elderly humans" 283 (283): c289-295, 2002

      34 Nieman,D.C., "Cytokine changes after a marathon race" 91 (91): 109-114, 2001

      35 Suzuki,K., "Circulating cytokines and hormones with immunosuppressive but neutrophilpriming potentials rise after endurance exercise in humans" 81 (81): 281-287, 2000

      36 Ostrowski,K., "Chemokines are elevated in plasma after strenuous exercise in humans" 84 (84): 244-245, 2001

      37 Starkie,R.L., "Carbohydrate ingestion attenuates the increase in plasma interleukin-6, but not skeletal muscle interleukin-6 mRNA, during exercise in humans" 533 (533): 585-591, 2001

      38 Das,U.N., "Anti-inflammatory nature of exercise" 20 (20): 323-326, 2004

      39 Ostrowski,K., "A traumalike elevation of plasma cytokines in humans in response to treadmill running" 153 (153): 889-894, 1998

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2026 평가예정 재인증평가 신청대상 (재인증)
      2020-01-01 평가 등재학술지 유지 (재인증) KCI등재
      2017-01-01 평가 등재학술지 유지 (계속평가) KCI등재
      2013-01-01 평가 등재 1차 FAIL (등재유지) KCI등재
      2010-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2007-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      2006-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2005-09-23 학술지등록 한글명 : 한국생활환경학회지
      외국어명 : The Korean Society of Living Environmental System
      KCI등재후보
      2004-07-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.29 0.29 0.28
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.31 0.3 0.376 0.11
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