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      KCI등재후보

      중심 측두엽 극파 동반 양성 간질에서의 인지 행동 관찰 및 topiramate 1일 1회 투약효과 = Cognitive and Behavioral Problems and the Effectiveness of Topiramate Once per Day in the Control of Benign Childhood Epilepsy with Centrotemporal Spikes

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      https://www.riss.kr/link?id=A99562289

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      다국어 초록 (Multilingual Abstract)

      Purpose : This study was aimed to evaluate cognitive and behavioral problems in benign childhood epilepsy with centrotemporal spikes (BECTS) using objective scales. In addition, we investigated the efficacy and cognitive effects of topiramate by intro- ducing it once a day as a pilot study. Methods : Seven patients were evaluated. They were diagnosed as BECTS based on clinical features and electroencephalography findings. We assessed cognitive and behavioral functions with several neuropsychological tests and followed up the sei- zure frequency, side effects, and cognitive dysfunction for six months after intro- ducing topiramate once per day. Results : The mean intelligence quotient, memory quotient, and social quotient of patients show the difference as compared to the general population. However, three patients showed attention deficit/hyperactivity disorder. Further, the seizure reduc- tion rate was 100% after receiving topiramate once a day and there were no newly reported neuropsychological problems on questionnaires. Conclusion : This study demonstrated that a significant number of children with BECTS have behavioral problems and that topiramate monotherapy once a day is effective.
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      Purpose : This study was aimed to evaluate cognitive and behavioral problems in benign childhood epilepsy with centrotemporal spikes (BECTS) using objective scales. In addition, we investigated the efficacy and cognitive effects of topiramate by intro...

      Purpose : This study was aimed to evaluate cognitive and behavioral problems in benign childhood epilepsy with centrotemporal spikes (BECTS) using objective scales. In addition, we investigated the efficacy and cognitive effects of topiramate by intro- ducing it once a day as a pilot study. Methods : Seven patients were evaluated. They were diagnosed as BECTS based on clinical features and electroencephalography findings. We assessed cognitive and behavioral functions with several neuropsychological tests and followed up the sei- zure frequency, side effects, and cognitive dysfunction for six months after intro- ducing topiramate once per day. Results : The mean intelligence quotient, memory quotient, and social quotient of patients show the difference as compared to the general population. However, three patients showed attention deficit/hyperactivity disorder. Further, the seizure reduc- tion rate was 100% after receiving topiramate once a day and there were no newly reported neuropsychological problems on questionnaires. Conclusion : This study demonstrated that a significant number of children with BECTS have behavioral problems and that topiramate monotherapy once a day is effective.

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      목차 (Table of Contents)

      • 서 론
      • 대상 및 방법
      • 결 과
      • 고 찰
      • 요 약
      • 서 론
      • 대상 및 방법
      • 결 과
      • 고 찰
      • 요 약
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      참고문헌 (Reference)

      1 Wheless JW, "Treatment of pediatric epilepsy:European expert opinion, 2007" 9 : 353-412, 2007

      2 Bootsma HP, "Topiramate in clinical practice: long-term experience in patients with refractory epilepsy referred to tertiary epilepsy center" 5 : 380-387, 2004

      3 Galanopoulou AS, "The spectrum of neuropsychiatric abnormalities associated with electrical status epilepticus in sleep" 22 : 279-295, 2000

      4 HC Kang, "The effects on cognitive function and behavioral problems of topiramate compared to carbamazepine as monotherapy for children with benign rolandic epilepsy" 48 : 1716-1723, 2007

      5 Papazian O, "The effect of interictal epileptiform discharges on cognitive function in children with idiopathic epilepsy" 36 : 282-284, 2003

      6 Binnie CD, "Significance and management of transitory cognitive impairment due to subclinical EEG discharges in children" 15 : 23-30, 1993

      7 Morikawa T, "Rolandic discharges in benign childhood epilepsy with centrotemporal spikes, and in other forms of partial epilepsies" 2 (2): s23-e28, 2002

      8 Arroyo S, "Randomized dose-controlled study of topiramate as first-line therapy in epilepsy" 112 : 214-222, 2005

      9 Commission on classification and terminology of the International League Against Epilepsy, "Proposal for classification of epilepsy and epileptic syndromes" 30 : 389-399, 1989

      10 Loiseau P, "Prognosis of benign childhood epilepsy with centrotemporal spikes : a follow-up study of 168 patients" 29 : 229-235, 1988

      1 Wheless JW, "Treatment of pediatric epilepsy:European expert opinion, 2007" 9 : 353-412, 2007

      2 Bootsma HP, "Topiramate in clinical practice: long-term experience in patients with refractory epilepsy referred to tertiary epilepsy center" 5 : 380-387, 2004

      3 Galanopoulou AS, "The spectrum of neuropsychiatric abnormalities associated with electrical status epilepticus in sleep" 22 : 279-295, 2000

      4 HC Kang, "The effects on cognitive function and behavioral problems of topiramate compared to carbamazepine as monotherapy for children with benign rolandic epilepsy" 48 : 1716-1723, 2007

      5 Papazian O, "The effect of interictal epileptiform discharges on cognitive function in children with idiopathic epilepsy" 36 : 282-284, 2003

      6 Binnie CD, "Significance and management of transitory cognitive impairment due to subclinical EEG discharges in children" 15 : 23-30, 1993

      7 Morikawa T, "Rolandic discharges in benign childhood epilepsy with centrotemporal spikes, and in other forms of partial epilepsies" 2 (2): s23-e28, 2002

      8 Arroyo S, "Randomized dose-controlled study of topiramate as first-line therapy in epilepsy" 112 : 214-222, 2005

      9 Commission on classification and terminology of the International League Against Epilepsy, "Proposal for classification of epilepsy and epileptic syndromes" 30 : 389-399, 1989

      10 Loiseau P, "Prognosis of benign childhood epilepsy with centrotemporal spikes : a follow-up study of 168 patients" 29 : 229-235, 1988

      11 Ambrosetto G, "Predictive factors of seizure frequency and duration of anti-epileptic treatment in rolandic epilepsy" 9 : 300-304, 1987

      12 Tatum WO 4th, "Postmarketing experience with topiramate and cognition" 42 : 1134-1140, 2001

      13 Weglage J, "Neuropsychological, intellectual, and behavioral findings in patient with and without seizure" 39 : 645-651, 1997

      14 Croona C, "Neuropsychological findings in children with benign childhood epilepsy with centrotemporal spikes" 41 : 813-818, 1999

      15 D’Alessandro P, "Neuropsychological features of benign partial epilepsy in children" 11 : 265-269, 1990

      16 Baglietto MG, "Neuropsychological disorders related to interictal epileptic discharges during sleep in benign epilepsy of childhood with centrotemporal or rolandic spikes" 43 : 407-412, 2001

      17 Monjauze C, "Language in benign childhood epilepsy with centrotemporal spikes abbreviated form:Rolandic epilepsy and language" 92 : 300-308, 2005

      18 Corda D, "Incidence of drug induced aggravation in BECTS" 42 : 754-759, 2001

      19 Chevalier H, "Impulsivity and control of inhibition in benign focal childhood epilepsy" 3 : 86-90, 2000

      20 Pan A, "Epileptiform discharges in benign focal epilepsy of childhood" 2 (2): s29-e36, 2002

      21 Camfield P, "Epileptic syndromes in childhood: Clinical features, outcomes, and treatment" 43 : 27-32, 2002

      22 Massa R, "EEG criteria predictive of complicated evolution in idiopathic rolandic epilepsy" 57 : 1071-1079, 2001

      23 Hommet C, "Cognitive function in adolescents and young adults in complete remission from benign epilepsy with centrotemporal spikes" 3 : 207-216, 2001

      24 Lee HW, "Cognitive effects of low-dose topiramate monotherpay in epilepsy patients: A 1-year follow-up" 8 : 736-741, 2006

      25 Yung AW, "Cognitive and behavioral problems in children with centrotemporal spikes" 23 : 391-395, 2000

      26 Gündüz E, "Benign rolandic epilepsy:neuropsychological findings" 8 : 246-249, 1999

      27 Lerman P, "Benign focal epilepsy of childhood: a follow up study of 100 recovered patients" 32 : 261-264, 1975

      28 Heijbel J, "Benign epilepsy of childhood school adjustment" 16 : 679-687, 1975

      29 Loiseau P, "Benign childhood epilepsy with centrotemporal spikes" 56 (56): 17-22, 1989

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2019 평가예정 신규평가 신청대상 (신규평가)
      2018-12-01 평가 등재후보 탈락 (계속평가)
      2016-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
      2012-01-01 평가 등재후보 탈락 (등재후보1차)
      2010-01-01 평가 등재후보 1차 FAIL (등재후보1차) KCI등재후보
      2008-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.17 0.17 0.17
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.16 0.14 0.384 0.02
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