아마인유와 해바라기 종자유의 혼합급이가 고지혈증 흰쥐의 폐조직 지질의 지방산조성에 미치는 영향 = Effects of Feeding the Mixture of Linseed and Sunflower Seed oil on the Fatty acid Composition of lung lipid in Dietary Hyperlipidermic Rats

다국어 초록 (Multilingual Abstract)

This study was carried out to investigate the effect of the feeding mixture of linseed oil, rich in n-3 PUFA and the sunflower seed oil, rich in n-6 PUFA on the fatty acid composition in the dietary hyperlipidermic rats. After Male Sprague Dawley rats were induced hyperlipidermia by feeding the diet containing lard, butter and cholesterol for 3 weeks, then they were fed with the diet containing lard 3 0% and butter 12 0% for control the mixture in different proportion of both linseed oil and sunflower seed oil and antihyperlipidermic drugs for 2 weeks. Analysis of the lipid composition and the fatty acid composition of the lung lipid showed following results.
In the total fatty acid contents of lung lipids, saturates were remarkedly more than monoenes and polyenes, while there were not significant different among total diet groups. Polyenes of the total fatty acid were not distributed C_(18:2), C_(18:3) on test lipid. but it were distributed on C_(20:4)(n-6), C_(20:5)(n-3), C_(22:5)(n-3), C_(22:6)(n-3) on lung tissue feed hyperlpidermic rats. In the fatty acid composition of phospholipid in lung, polyene contents of group 1-4 feed test lipid were 5.5 - 7.3% but increased to 25.7 - 28.9% in lung lipid of hyperlidermic rats In the fatty acid composition of triglyceride, TG content of group 5-9 feed mixed linseed oil and sunflower oil were getting higher than group1-4 feed butter or olive oil and it seems to be affected to anti-atherosclerosis. In the fatty acid composition of C E were remarkedly significant different among monoencs, saturates and polyenes in test lipid but it was different tendency in lung lipid of hyperlipidermic rats C_(20.5)(n-3) was the major fatty acid in total fatty acid and PL while C_(18.2)(n-6) was the major fatty acid in total fatty acid, TG and C E of lung lipid Each lipid composition was comparatively influenced test lipid rather than cholestyramine and antihyperlipidermic dose. Sunflower seed oil and linseed oil were effective for the improvement of lung lipids.