클로르헥시딘과 테트라사이클린의 치주낭 세척 효과 = THE EFFECT OF SUBGINGIVAL IRRIGATION WITH CHLORHEXIDINE AND TETRACYCLINE

다국어 초록 (Multilingual Abstract)

This study aimed to evaluate the influence of subgingival irrigation with chlorhexidine and tetracycline on the effect of scaling and root planing in periodontal treatment. Fifty six sites, 5㎜ or greater in probing depth from selected patients, were divided into 4 groups : Group Ⅰ - chlorhexidine(0.1%) irrigation after scaling and root planing ; Group Ⅱ - tetracycline(0.5%) irrigation after scaling and root planing ; Group Ⅲ - saline irrigation after scaling and root planing and Group Ⅳ - scaling and root planing alone.
Following thorough scaling and root planing irrigation was done and repeated every other day during two weeks for group Ⅰ, Ⅱ and Ⅲ. Clinical and microbiological monitorings were done immediately before scaling and root planing and at 2, 4, 8 and 12 weeks after scaling and root planing. Clinically, plaque index(Silness and Lo¨e), gingival crevicular fluid amount, probing depth, sulcus bleeding index(Mu¨hlemann and Son) and attachment level were recorded. Microbiologically, trypsin-like enzyme activity of subgingival microflora was monitored using benzoyl-arginine naphthylamide test.
The results were as follows:
1. Plaque index score and attachment level showed no significant difference among the 4 experimental groups and during all the experimental periods.
2. Gingival crevicular fluid amount and probing depth showed significant decrease in irrigated group (Group Ⅰ, Ⅱ and Ⅲ) from week 2, and in scaling and root planing only group (Group Ⅳ) from week 4.
3. Sulcus bleeding index score in each experimental group decreased significantly during all the experimental periods.
4. The trypsin-like enzyme activity in subgingival microflora in each experimental group decreased significantly during all the experimental periods. The results suggest that the subgingival irrigation in the presence of thorough scaling and root planing has beneficial effect to the reduction in gingival crevicular fluid flow and probing depth in early post-treatment period and the antimicrobial irrigation has no additive effect.

목차 (Table of Contents)

• Ⅰ. 서 론
• Ⅱ. 대상 및 방법
• Ⅲ. 성 적
• Ⅳ. 고 찰
• Ⅴ. 결 론
• 참고문헌
• 영문초록