양하 꽃대의 생리활성 및 양갱 제조

국문 초록 (Abstract)

본 연구에서는 폐경 이후 발생률이 높은 심혈관계 질환 예방에 도움을 줄 수 있는 식품을 개발할 목적으로 PDGF-BB로 혈관평활근세포의 이주와 증식을 유도한 다음 양하 꽃대 추출물이 혈관평활근세포의 이주와 증식에 미친 억제 효과를 알아보았다. 그리고 양하 꽃대 시료를 첨가한 양갱을 제조하여 그 품질 특성을 평가, 최적 비율의 양하 꽃대 양갱을 확인하고자 하였다. 혈관평활근세포의 이주에서는 양하 꽃대 추출물 100 μg/mL에서부터 정상세포와 유사한 수준을 나타냈다. 또한 증식에서는 양하 꽃대 추출물 10 μg/mL에서부터 확연히 억제되어 1,000 μg/mL에서는 정상세포 수준까지 떨어졌다. 양하 양갱의 경우 양하 꽃대 시료 첨가량이 높아질수록 명도와 황색도는 유의적(P<0.05)으로 감소한 반면 적색도는 증가하였다. 양하 꽃대를 이용한 양갱의 관능 평가 결과를 종합해보면 양하 꽃대 시료 9 g 첨가군(YY9)에서 가장 높은 점수가 나타났다. 양하 꽃대는 항산화 활성 향상과 혈관평활근세포의 이주와 증식을 억제하는 작용이 나타났으므로, 혈관 손상을 예방해줄 수 있는 기능성식품으로서의 가능성을 확인하였다. 따라서 관능평가에서 우수한 점수를 보여준 양하 꽃대 시료 9 g 첨가 양하 양갱은 중년여성의 심혈관질환 예방에 도움을 줄 수 있는 식품으로 기대된다.

다국어 초록 (Multilingual Abstract)

This study was performed to investigate the biological activity of yangha flower buds as well as to manufacture of yanggeng prepared with various levels (0 g, 3 g, 6 g, 9 g, and 12 g) of yangha flower buds. DPPH and ABTS scavenging activities of yangha flower buds were 96% and 57% compared to levels of vitamin C, respectively. In the oxygen radical antioxidant capacity assay, antioxidant activity increased dose dependently up to 500 μg/mL of yangha flower buds. There was no toxicity up to 1,000 μg/mL in vascular smooth muscle cells, and yanggeng significantly reduced migration and proliferation by platelet-derived growth factor-BB-stimulated rat aortic smooth muscle cell migration and proliferation. In the sensory evaluation, the optimal sample was YY9, which was prepared with 9 g of yangha flower buds. It can be concluded that yangha flower buds show antioxidant and vascular protective activities. The optimal sample (YY9) is expected to contribute as a new functional food.

목차 (Table of Contents)

• ABSTRACT
• 서론
• 재료 및 방법
• 결과 및 고찰
• 요약
• REFERENCES

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