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      KCI등재 SCOPUS

      라섹 술중 잘못 사용된 고농도 마이토마이신 C에 의한 각막혼탁 = Corneal Opacity Caused by LASEK with Improper High-concentrated Mitomycin-C

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      https://www.riss.kr/link?id=A100523484

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      다국어 초록 (Multilingual Abstract)

      Purpose: To report a case of corneal opacity with postoperative changes of topographic features and visual acuity after laser subepithelial keratomileusis (LASEK) treated with an improper concentration of mitomycin-C. Case summary: A 25-year-old female patient who experienced corneal opacity after LASEK treated with mitomycin-C was evaluated for changes in corneal opacity by photography, central corneal power by Orb scan Ⅱz, and best corrected visual acuity (BCVA) over the period of 1 year. The corneal epithelial defect was completely healed 2 weeks after the LASEK operation. Subepithelial and stromal opacity decreased over time, but her cornea did not return to normal. BCVA was 20/25 in the right eye and 20/20 in the left eye at postoperative 1 year, but stromal opacity remained. Conclusions: An improper concentration of mitomycin-C during LASEK could result in corneal opacity. Long time is needed to recover visual acuity and a normal corneal structure. J Korean Ophthalmol Soc 2008;49(9):1525-1531
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      Purpose: To report a case of corneal opacity with postoperative changes of topographic features and visual acuity after laser subepithelial keratomileusis (LASEK) treated with an improper concentration of mitomycin-C. Case summary: A 25-year-old femal...

      Purpose: To report a case of corneal opacity with postoperative changes of topographic features and visual acuity after laser subepithelial keratomileusis (LASEK) treated with an improper concentration of mitomycin-C. Case summary: A 25-year-old female patient who experienced corneal opacity after LASEK treated with mitomycin-C was evaluated for changes in corneal opacity by photography, central corneal power by Orb scan Ⅱz, and best corrected visual acuity (BCVA) over the period of 1 year. The corneal epithelial defect was completely healed 2 weeks after the LASEK operation. Subepithelial and stromal opacity decreased over time, but her cornea did not return to normal. BCVA was 20/25 in the right eye and 20/20 in the left eye at postoperative 1 year, but stromal opacity remained. Conclusions: An improper concentration of mitomycin-C during LASEK could result in corneal opacity. Long time is needed to recover visual acuity and a normal corneal structure. J Korean Ophthalmol Soc 2008;49(9):1525-1531

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      참고문헌 (Reference)

      1 이제혁, "가토에서 Mitomycin C가 엑시머 레이저 각막절삭술 후 창상치유에 미치는 영향" 대한안과학회 44 (44): 2876-2884, 2003

      2 Majmudar PA, "Topical mitomycin-C for subepithelial fibrosis after refractive corneal surgery" 107 : 89-94, 2000

      3 Wilson SE, "The wound healing response after laser in situ keratomileusis and photorefractive keratectomy; elusive control of biological variability an effect of custom laser vision correction" 119 : 889-896, 2001

      4 Moller-Pederson TM, "Stromal wound healing explains refractive instability and haze development after photorefractive keratectomy: a 1-year confocal microscopic study" 107 : 1235-1245, 2000

      5 Kaji Y, "Relation between corneal haze and transforming growth factor- β1 after photorefractive keratectomy and laser in situ keratomileusis" 27 : 1840-1846, 2001

      6 Lin N, "Prediction of corneal haze using an ablation depth/corneal thickness ratio after alser epithelial keratomileusis" 20 : 797-802, 2004

      7 Alio JL, "Postoperative inflammation, microbial complication, and wound healing following laser in situ keratomileusis" 16 : 523-538, 2000

      8 Talamo JH, "Modulation of corneal wound healing after excimer laser keratomileusis using topical mitomycin C and steroids" 109 : 1141-1146, 1991

      9 Gambato C, "Mitomycin Cmodulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes" 12 : 208-218, 2005

      10 Xu H, "Mitomycin C reduces haze formation in rabbits after excimer laser photorefractive keratectomy" 17 : 342-349, 2001

      1 이제혁, "가토에서 Mitomycin C가 엑시머 레이저 각막절삭술 후 창상치유에 미치는 영향" 대한안과학회 44 (44): 2876-2884, 2003

      2 Majmudar PA, "Topical mitomycin-C for subepithelial fibrosis after refractive corneal surgery" 107 : 89-94, 2000

      3 Wilson SE, "The wound healing response after laser in situ keratomileusis and photorefractive keratectomy; elusive control of biological variability an effect of custom laser vision correction" 119 : 889-896, 2001

      4 Moller-Pederson TM, "Stromal wound healing explains refractive instability and haze development after photorefractive keratectomy: a 1-year confocal microscopic study" 107 : 1235-1245, 2000

      5 Kaji Y, "Relation between corneal haze and transforming growth factor- β1 after photorefractive keratectomy and laser in situ keratomileusis" 27 : 1840-1846, 2001

      6 Lin N, "Prediction of corneal haze using an ablation depth/corneal thickness ratio after alser epithelial keratomileusis" 20 : 797-802, 2004

      7 Alio JL, "Postoperative inflammation, microbial complication, and wound healing following laser in situ keratomileusis" 16 : 523-538, 2000

      8 Talamo JH, "Modulation of corneal wound healing after excimer laser keratomileusis using topical mitomycin C and steroids" 109 : 1141-1146, 1991

      9 Gambato C, "Mitomycin Cmodulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes" 12 : 208-218, 2005

      10 Xu H, "Mitomycin C reduces haze formation in rabbits after excimer laser photorefractive keratectomy" 17 : 342-349, 2001

      11 Pushker N, "Microbial keratitis after laser in situ keratomuleusis" 18 : 280-286, 2002

      12 Carones F, "Mechanical vs alcohol epithelial removal during photorefractive keratectomy" 15 : 556-562, 1999

      13 Autrata R, "Laser-assisted subepithelial keratectomy and photorefractive keratectomy for the correction of hyperopia: results of a 2-year follow-up" 29 : 2105-2114, 2003

      14 Carones F, "Evaluation of the prophylactic use of mitomycin-C to inhibit haze formation after photorefractive keratectomy" 28 : 2088-2095, 2002

      15 Kim TI, "Evaluation for Safety of cultured Corneal Fibroblasts with Cotreatment of Alcohol and Mitomycin C" 45 : 86-92, 2004

      16 Kim KS, "Endothelial cell change after photorefractive keratectomy and laser in situ keratomileusis" 40 : 2728-2734, 1999

      17 Chang SW, "Early corneal edema folllowing topical application of mitomycin-C" 30 : 1742-1750, 2004

      18 Laplace O, "Early bacterial keratitis after laser-assisted subepithelial keratectomy" 30 : 2638-2640, 2004

      19 Linebarger EJ, "Diffuse lamellar keratitis:diagnosis and management" 26 : 1072-1077, 2000

      20 Quazi MA, "Development of late-onset subepithelial corneal haze after laser-assisted subepithelial keratectomy with prophylactic intraoperative mitomycin-C" 32 : 1573-1578, 2006

      21 Sonmez B, "Central toxic keratopathy:Description of a syndrome in laser refractive surgery" 143 : 420-427, 2007

      22 Cobett MC, "An in vivo investigation of the structures responsible for corneal haze after photorefractive keratectomy and their effect on visual function" 103 : 1366-1380, 1996

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      연월일 이력구분 이력상세 등재구분
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      2020-01-01 평가 등재학술지 유지 (해외등재 학술지 평가) KCI등재
      2017-01-01 평가 등재학술지 유지 (계속평가) KCI등재
      2013-01-01 평가 등재 1차 FAIL (등재유지) KCI등재
      2010-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2007-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      2006-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2005-01-01 평가 등재후보학술지 유지 (등재후보1차) KCI등재후보
      2003-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.22 0.22 0.22
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.23 0.23 0.366 0.02
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