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      Pravastatin에 의한 스티븐스-존슨증후군 1예 = CASE REPORT : Pravastatin-induced Stevens-Johnson syndrome

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      https://www.riss.kr/link?id=A101573161

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      다국어 초록 (Multilingual Abstract)

      Stevens-Johnson syndrome (SJS) manifests with severe cutaneous reactions, most commonly triggered by medications, which are characterized by fever and mucocutaneous lesions leading to necrosis and sloughing of the epidermis. To our knowledge, pravastatin- induced SJS has not yet been reported. Here, we describe a case of SJS due to pravastatin, which was diagnosed by a patch test. A 70-year-old woman presented with maculopapular skin rashes, which developed 2 weeks after medication of bisoprolol, amlodipine, pravastatin, spironolactone, and indobufene for cardiac problems. Various bullous-erosive mucocutaneous lesions occupied less than 10% of the total body surface area. Painful oropharyngeal mucous membrane lesions were observed. The vermilion border of the lips became denuded and developed serosanguinous crusts. With the drug withdrawal and the use of systemic corticosteroids, her manifestations resolved. Drug patch tests with bisoprolol, amlodipine, pravastatin, spironolactone, and indobufene were performed, resulting in a positive reaction to pravastatin, but not to the other drugs. To the best of our knowledge, this is the first case of pravastatin-induced SJS. (Allergy Asthma Respir Dis 2015;3:446-448)
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      Stevens-Johnson syndrome (SJS) manifests with severe cutaneous reactions, most commonly triggered by medications, which are characterized by fever and mucocutaneous lesions leading to necrosis and sloughing of the epidermis. To our knowledge, pravasta...

      Stevens-Johnson syndrome (SJS) manifests with severe cutaneous reactions, most commonly triggered by medications, which are characterized by fever and mucocutaneous lesions leading to necrosis and sloughing of the epidermis. To our knowledge, pravastatin- induced SJS has not yet been reported. Here, we describe a case of SJS due to pravastatin, which was diagnosed by a patch test. A 70-year-old woman presented with maculopapular skin rashes, which developed 2 weeks after medication of bisoprolol, amlodipine, pravastatin, spironolactone, and indobufene for cardiac problems. Various bullous-erosive mucocutaneous lesions occupied less than 10% of the total body surface area. Painful oropharyngeal mucous membrane lesions were observed. The vermilion border of the lips became denuded and developed serosanguinous crusts. With the drug withdrawal and the use of systemic corticosteroids, her manifestations resolved. Drug patch tests with bisoprolol, amlodipine, pravastatin, spironolactone, and indobufene were performed, resulting in a positive reaction to pravastatin, but not to the other drugs. To the best of our knowledge, this is the first case of pravastatin-induced SJS. (Allergy Asthma Respir Dis 2015;3:446-448)

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      참고문헌 (Reference)

      1 Adams AE, "Statins and"chameleon-like"cutaneous eruptions : simvastatin-induced acral cutaneous vesiculobullous and pustular eruption in a 70-year-old man" 14 : 207-211, 2010

      2 Petrou E, "Simvastatin-induced toxic epidermal necrolysis" 335-336, 2014

      3 Hydzik P, "Side effects of the HMG-CoA reductase inhibitors (statins). Lupus erythematosus induced by Atorvastatin therapy" 68 : 495-498, 2011

      4 Peters AT, "Patterson's allergic diseases" 232-235, 2009

      5 Wolkenstein P, "Patch testing in severe cutaneous adverse drug reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis" 35 : 234-236, 1996

      6 Fregert S, "Manual of contact dermatitis" Munksgaard Publishers 1981

      7 Tas S, "Management of drug rash with eosinophilia and systemic symptoms(DRESS syndrome) : an update" 206 : 353-356, 2003

      8 Wolf R, "Drug Rash with eosinophilia and systemic symptoms versus Stevens-Johnson Syndrome : a case that indicates a stumbling block in the current classification" 141 : 308-310, 2006

      9 Gressier L, "Atorvastatin-induced drug reaction with eosinophilia and systemic symptoms(DRESS)" 136 : 50-53, 2009

      1 Adams AE, "Statins and"chameleon-like"cutaneous eruptions : simvastatin-induced acral cutaneous vesiculobullous and pustular eruption in a 70-year-old man" 14 : 207-211, 2010

      2 Petrou E, "Simvastatin-induced toxic epidermal necrolysis" 335-336, 2014

      3 Hydzik P, "Side effects of the HMG-CoA reductase inhibitors (statins). Lupus erythematosus induced by Atorvastatin therapy" 68 : 495-498, 2011

      4 Peters AT, "Patterson's allergic diseases" 232-235, 2009

      5 Wolkenstein P, "Patch testing in severe cutaneous adverse drug reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis" 35 : 234-236, 1996

      6 Fregert S, "Manual of contact dermatitis" Munksgaard Publishers 1981

      7 Tas S, "Management of drug rash with eosinophilia and systemic symptoms(DRESS syndrome) : an update" 206 : 353-356, 2003

      8 Wolf R, "Drug Rash with eosinophilia and systemic symptoms versus Stevens-Johnson Syndrome : a case that indicates a stumbling block in the current classification" 141 : 308-310, 2006

      9 Gressier L, "Atorvastatin-induced drug reaction with eosinophilia and systemic symptoms(DRESS)" 136 : 50-53, 2009

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2026 평가예정 재인증평가 신청대상 (재인증)
      2020-01-01 평가 등재학술지 유지 (재인증) KCI등재
      2017-01-01 평가 등재학술지 선정 (계속평가) KCI등재
      2016-12-01 평가 등재후보로 하락 (계속평가) KCI등재후보
      2013-04-05 학술지명변경 한글명 : 대한소아알레르기및호흡기학회지 -> Allergy Asthma & Respiratory Diseases
      외국어명 : THE Korean Academy of Pediatric Allergy and Respiratory Disease -> 알레르기 천식 호흡기질환
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      2010-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2009-01-01 평가 등재 1차 FAIL (등재유지) KCI등재
      2007-05-30 학회명변경 한글명 : 대한소아알레르기 및 호흡기학회 -> 대한 소아알레르기 호흡기학회 KCI등재
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      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.34 0.34 0.49
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.41 0.41 0.971 0.19
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