DNA Polymorphism in 5'-Flanking Region of Human Apolipoprotein A1 and Glutathione S-transferase Mul Gene in Koreans : (Botrytis cinerea와 기주간의 상호작용 및 Allomyces macrogynous 발달과정의 세포, 생리학적 연구)

다국어 초록 (Multilingual Abstract)

The distributions of G to A substitution (G^-75 ?A) mutation in the human apolipoprotein Al (APOA1) gene promoter region and glutathions S-tran-sferase Mu1 (GSTM1) gene deletion were examined in subjects with Korean population. The G^-75 ?A mutation of APOA1 was genotyped by the poly-merass chain reaction (PCR) and subsequent digestion of the PCR product using either Msp1 or Mva1 (n=206). The observed numbers of GG, GA and AA genotypes were 132, 63 and 11, respectively. The allele frequencies of G and A were 0.794 and 0.206, respectively. The GSTM1 gene deletion was simply examined by the PCR amplification (n=106). The observed numbers of null type (GSTM1*0/GSTM1*0) and positive type were 55 and 51, respectively. The allels frequency of GSTM1*0 was 0.720.

목차 (Table of Contents)

• 1.Materials and Methods
• 2.Results
• 3.Discussion
• 4.References