고콜레스테롤혈증 흰쥐의 유리지방산, Creatine Phosphokinase 및 LCAT 활성에 돌복숭아(Prunus persica Batsch var.davidiana Max.)추출액이 미치는 영향 = Effects of Prunus persica Batsch var. davidiana Max. Extract on the Free Fatty Acid, Creatine Phosphokinase and LCAT Activities in Hypercholesterolemic Rats

다국어 초록 (Multilingual Abstract)

This study was performed to observe the effects of the feeding Prunus persica Batsch var. davidiana Max. extract on the improvement of the free fatty acid, creatine phosphokinase and lecithin cholesterol acyltransferase(LCAT) activities in the serum of dietary hypercholesterolemic rats(S. D. strain, male) fed the experimental diets for 5 weeks. Concentration of electrolyte(Na, K, Cl) in serum were fairly reduced in the group BCP(basal diet + cholesterol + Prunus persica, 5.0 g% extract) than in the group BCW(basal diet + cholesterol + water). However, no significance was found in the effect of an electrolyte concentration among the groups. Concentrations of free fatty acid, lipid peroxide and creatine phosphokinase activity in serum were significantly higher in the cholesterol administration groups(group BCW, BCP) than those in the control group(group BW, basal diet + water). However, concentrations of free fatty acid, lipid peroxide and creatine phosphokinase activity in serum were remarkably lower in the group BCP than those in the group BCW. The LCAT activity in serum was increased in the Prunus persica 5.0 g% extract administration group(group BCP) than in the cholesterol diet group(group BCW). From these results, the Prunus persica Batsch var. davidiana Max. extracts were found to be effective on the improvement of the lipid compositions in serum of dietary hypercholesterolemic rats.

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