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      망막 회복을 위한 줄기세포 및 조직공학의 연구동향 = Feature Article : Stem Cell and Tissue Engineering for Retinal Repair

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      https://www.riss.kr/link?id=A99577417

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      다국어 초록 (Multilingual Abstract)

      The retinal disorder in which it shows up while an age gives is caused by a heredity and altitude myopia, a debit, and etc. and it causes the blind. Although retinal disorder is not disease in which fatal disease leads, in including a diabetes, and etc, the retina disease in which it can become with provoke is the trend that recently it is drastically increased along with the increment of the population of old people according to the change of an industrialization and dietary life. However, as to the current retinal disorder, there is a limit. For this reason, the medical treatment of the method in which directly transplant the nerve cells or the glial cells differentiated from the stem cell and retina precursor cell into retina, and the tissue engineered therapy of the neural retina in which it implants into a retina to the tissue engineering technique in which use these cells and biomaterials have been studied. The current review looks into clinical methods and studies on cell and tissue engineering therapy for the retinal disorder.
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      The retinal disorder in which it shows up while an age gives is caused by a heredity and altitude myopia, a debit, and etc. and it causes the blind. Although retinal disorder is not disease in which fatal disease leads, in including a diabetes, and et...

      The retinal disorder in which it shows up while an age gives is caused by a heredity and altitude myopia, a debit, and etc. and it causes the blind. Although retinal disorder is not disease in which fatal disease leads, in including a diabetes, and etc, the retina disease in which it can become with provoke is the trend that recently it is drastically increased along with the increment of the population of old people according to the change of an industrialization and dietary life. However, as to the current retinal disorder, there is a limit. For this reason, the medical treatment of the method in which directly transplant the nerve cells or the glial cells differentiated from the stem cell and retina precursor cell into retina, and the tissue engineered therapy of the neural retina in which it implants into a retina to the tissue engineering technique in which use these cells and biomaterials have been studied. The current review looks into clinical methods and studies on cell and tissue engineering therapy for the retinal disorder.

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      참고문헌 (Reference)

      1 2005 한국의 당뇨병, 건강보험심사평가원

      2 메디컬투데이/뉴시스, "실명치료, 대장암약 禿틜母뵈앞 안전한가"

      3 메디컬투데이/뉴시스, "실명 유발 황반변성, 6년 사이 7배 증가"

      4 함기선, "신경생리학" 현문사 1997

      5 머니투데이, "당뇨환자 눈 관리소홀, 더 큰 화 부른다"

      6 뉴시스헬스/뉴시스, "김안과병원, 毒존² 항체주사술’ 안전성 입증"

      7 KIST, "글로벌동향브리핑" 2003

      8 한치과의사협회, "구강막 이용 인공망막 배양 성공 환자에 이식해 시력 회복" 2003

      9 Nucleus Medical Art Inc., "http://www.nucleusinc.com"

      10 Neurotech, "http://www.neurotechusa.com"

      1 2005 한국의 당뇨병, 건강보험심사평가원

      2 메디컬투데이/뉴시스, "실명치료, 대장암약 禿틜母뵈앞 안전한가"

      3 메디컬투데이/뉴시스, "실명 유발 황반변성, 6년 사이 7배 증가"

      4 함기선, "신경생리학" 현문사 1997

      5 머니투데이, "당뇨환자 눈 관리소홀, 더 큰 화 부른다"

      6 뉴시스헬스/뉴시스, "김안과병원, 毒존² 항체주사술’ 안전성 입증"

      7 KIST, "글로벌동향브리핑" 2003

      8 한치과의사협회, "구강막 이용 인공망막 배양 성공 환자에 이식해 시력 회복" 2003

      9 Nucleus Medical Art Inc., "http://www.nucleusinc.com"

      10 Neurotech, "http://www.neurotechusa.com"

      11 Vitreoretinal Consultants, "http://www.houstonretina.com"

      12 정인안과, "http://www.chungeye.co.kr"

      13 American Health Assistance Foundation, "http://www.ahaf.org"

      14 인제대학교 안과학교실, "http://eyedori.pusanpaik.or.kr"

      15 American diabetes association, "all about diabetes"

      16 F Osakada, "Wnt signaling promotes regeneration in the retina of adult mammals" 27 : 4210-, 2007

      17 DA Lamba, "Transplantation of human embryonic stem cell-derived photoreceptors restores some visual function in crx-deficient mice" 4 : 73-, 2009

      18 F Osakada, "Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells" 26 : 215-, 2008

      19 G Thumann, "The in vitro and in vivo behaviour of retinal pigment epithelial cells cultured on ultrathin collagen membranes" 30 : 287-, 2009

      20 S Tao, "Survival, migration and differentiation of retinal progenitor cells transplanted on micromachined poly(methyl methacrylate) scaffolds to the subretinal space" 7 : 695-, 2007

      21 MJ Young, "Stem cells in the mammalian eye: a tool for retinal repair" 113 : 845-, 2005

      22 Prevent Blindness America, "Retinitis Pigmentosa"

      23 K Canola, "Retinal stem cells transplanted into models of late stages of retinitis pigmentosa preferentially adopt a glial or a retinal ganglion cell fate" 48 : 446-, 2007

      24 K Warfvinge, "Retinal progenitor cell xenografts to the pig retina: morphologic integration and cytochemical differentiation" 123 : 1385-, 2005

      25 P Castanheira, "Retinal incorporation and differentiation of mesenchymal stem cells intravitreally injected in the injured retina of rats" 71 : 644-, 2008

      26 G Khang, "Recent advances in artificial retinal implant" 5 : 388-, 2008

      27 J Cai, "Properties of a fetal multipotent neural stem cell (NEP cell)" 251 : 221-, 2002

      28 ND Radtke, "Preliminary report: indications of improved visual function after retinal sheet transplantation in retinitis pigmentosa patients" 128 : 384-, 1999

      29 TY Wong, "Population-based studies in ophth almology" 146 : 656-, 2008

      30 G Qiu, "Photoreceptor differentiation and integration of retinal progenitor cells transplanted into transgenic rats" 80 : 515-, 2005

      31 MA Ahmadi, "Pharmacotherapy of age-related macular degeneration" 9 : 3045-, 2008

      32 K Minamino, "Long-term survival of bone marrow-derived retinal nerve cells in the retina" 16 : 1255-, 2005

      33 M Abdouh, "In vivo reactivation of a quiescent cell population located in the ocular ciliary body of adult mammals" 83 : 153-, 2006

      34 A Tezcaner, "In vitro characterization of micropatterned PLGA-PHBV8 blend films as temporary scaffolds for photoreceptor cells" 86 : 170-, 2008

      35 MS Humayun, "Human neural retina transplantation" 41 : 3100-, 2000

      36 NT Raymond, "Higher prevalence of retinopathy in diabetic patients of south asian ethnicity compared with white europeans in the community" 32 : 410-, 2009

      37 PG Layer, "From stem cells towards neural layers: a lesson from re-aggregated embryonic retinal cells" 12 : 39-, 2001

      38 CB Mellough, "Fate of multipotent neural precursor cells transplanted into mouse retina selectively depleted of retinal ganglion cells" 186 : 6-, 2004

      39 EB Lavik, "Fabrication of degradable polymer scaffolds to direct the integration and differentiation of retinal progenitors" 26 : 3187-, 2005

      40 S Redenti, "Engineering retinal progenitor cell and scrollable poly(glycerol-sebacate) composites for expansion and subretinal transplantation" 2009

      41 K Dutt, "Engineering retina from human retinal progenitors(cell lines)" 2009

      42 A Kicic, "Differentiation of marrow stromal cells into photoreceptors in the rat eye" 23 : 7742-, 2003

      43 F Scintu, "Differentiation of human bone marrow stem cells into cells with a neural phenotype: diverse effects of two specific treatments" 7 : 14-, 2006

      44 DS Fong, "Diabetic retinopathy" 27 : 2540-, 2004

      45 PA Sieving, "Ciliary neurotrophic factor(CNTF) for human retinal degeneration: phase I trial of CNTF delivered by encapsulated cell intraocular implants" 103 : 3896-, 2006

      46 U Lendahl, "CNS stem cells express a new class of intermediate filament protein" 60 : 585-, 1990

      47 M Tomita, "Biodegradable polymer composite grafts promote the survival and differentiation of retinal progenitor cells" 23 : 1579-, 2005

      48 M Engelhardt, "Adult retinal pigment epithelium cells express neural progenitor properties and the neuronal precursor protein doublecortin" 1040 : 98-, 2005

      49 RY Tsai, "A nucleolar mechanism controlling cell proliferation in stem cell and cancer cells" 16 : 2991-, 2002

      50 WL Neeley, "A microfabricated scaffold for retinal progenitor cell grafting" 29 : 418-, 2008

      51 M Tomita, "A comparison of neural differentiation and retinal transplantation with bone marrowderived cells and retinal progenitor cells" 24 : 2270-, 2006

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      학술지등록 한글명 : 조직공학과 재생의학
      외국어명 : Tissue Engineering and Regenerative Medicine
      2023 평가예정 해외DB학술지평가 신청대상 (해외등재 학술지 평가)
      2020-01-01 평가 등재학술지 유지 (해외등재 학술지 평가) KCI등재
      2013-10-01 평가 등재학술지 선정 (기타) KCI등재
      2012-01-01 평가 등재후보 1차 FAIL (기타) KCI등재후보
      2011-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2010-01-01 평가 등재후보 1차 FAIL (등재후보1차) KCI등재후보
      2008-01-01 평가 SCIE 등재 (신규평가) KCI등재후보
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      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 1.08 0.42 0.81
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.69 0.51 0.367 0.03
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