급성순수외측연수경색에서 딸꾹질과 병변의 위치적 연관성

다국어 초록 (Multilingual Abstract)

Background: Intractable hiccup is not a frequent but disabling condition of lateral medullary infarction (LMI). Unlike other symptoms and signs of LMI, the anatomical lesions of intractable hiccup are not well known. Although there were studies about clinical-radiological correlation using MRI, few studies have evaluated the relation between lesional location of LMI and intractable hiccup. Therefore, we performed this study to clarify the lesional correlation with intractable hiccup in LMI. Methods: Between 1997 and 2003, we identified 12 patients with pure LMI (LMI without concomitant midbrain, pontine, cerebellar, or cerebral infarction) who presented with intractable hiccup in addition to typical lateral medullary syndrome. Eighteen patients without hiccup were included as control group. Clinical and radiologic findings were compared between two groups. Results: The patients with intractable hiccup significantly more often had dorsal lesions rather than ventral lesions at horizontal levels (P=0.011). But, there were no rostrocaudal differences at vertical levels. Conclusion: We suggest that pure LMI associated with intractable hiccup often locates in the dorsal medulla at horizontal correlation. This comparative study using MRI helps us to expand the understanding of the neural substrate for intractable hiccup in LMI. (Korean J Stroke 2008;10:30-35)

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