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      전립선 수술 술식에 따른 2세대 Cephalosporin계의 예방적 효과 = Prophylactic Effectiveness of Second Generation Cephalosporin According to Prostatic Operation Methods

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      https://www.riss.kr/link?id=A101573739

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      Purpose: There is no definitive standard concerning the use of prophylactic antibiotics for prostatic operations, except for transurethral resection of prostate (TUR-P). This study prospectively investigated the prophylactic effectiveness of a second generation cephalosporin according to prostatic operation method.
      Materials and Methods: From October 2010 to January 2011, prostatic operations were conducted for 67 patients: group I (radical prostatectomy, n=18), group II (TUR-P, n=38), group III (laser TUR-P, n=11) for 11: group III). Prophylactic antibiotics were intravenously administered beginning 1 hour preoperatively and orally with several days postoperatively. Prophylactic effectiveness was evaluated by comparison of urine analysis and presence of bacteriuria.
      Results: In group I, no patient had preoperative Foley catheter installation, and mean antibiotic prescription period pre- and post-operatively was 5.83 days and 6.94 days. Five group I patients (27.8%) displayed bacteriuria. In group II, 9 patients had preoperative Foley catheter installation and mean antibiotic prescription period was 3.76 days and 5.68 days, respectively. Five patients (13.2%) had postoperative bacteriuria; two in preoperative catheterized patients and three in preoperative non-catheterized patients. In group III, mean antibiotic prescription period was 1.73 days and 5.09 days, respectively. There was no postoperative bacteriuria.
      Conclusions: Prophylactic use of a second generation cephalosporin for prostatic operation, except laser TUR-P, was limited in preventing postoperative pyuria with bacteriuria. There was a tendency of higher occurrence of postoperative bacteriuria in patients with preoperative Foley catheter installation.
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      Purpose: There is no definitive standard concerning the use of prophylactic antibiotics for prostatic operations, except for transurethral resection of prostate (TUR-P). This study prospectively investigated the prophylactic effectiveness of a second ...

      Purpose: There is no definitive standard concerning the use of prophylactic antibiotics for prostatic operations, except for transurethral resection of prostate (TUR-P). This study prospectively investigated the prophylactic effectiveness of a second generation cephalosporin according to prostatic operation method.
      Materials and Methods: From October 2010 to January 2011, prostatic operations were conducted for 67 patients: group I (radical prostatectomy, n=18), group II (TUR-P, n=38), group III (laser TUR-P, n=11) for 11: group III). Prophylactic antibiotics were intravenously administered beginning 1 hour preoperatively and orally with several days postoperatively. Prophylactic effectiveness was evaluated by comparison of urine analysis and presence of bacteriuria.
      Results: In group I, no patient had preoperative Foley catheter installation, and mean antibiotic prescription period pre- and post-operatively was 5.83 days and 6.94 days. Five group I patients (27.8%) displayed bacteriuria. In group II, 9 patients had preoperative Foley catheter installation and mean antibiotic prescription period was 3.76 days and 5.68 days, respectively. Five patients (13.2%) had postoperative bacteriuria; two in preoperative catheterized patients and three in preoperative non-catheterized patients. In group III, mean antibiotic prescription period was 1.73 days and 5.09 days, respectively. There was no postoperative bacteriuria.
      Conclusions: Prophylactic use of a second generation cephalosporin for prostatic operation, except laser TUR-P, was limited in preventing postoperative pyuria with bacteriuria. There was a tendency of higher occurrence of postoperative bacteriuria in patients with preoperative Foley catheter installation.

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      참고문헌 (Reference)

      1 유광호, "최근 요로감염증의 주요 원인균과 항생제 감수성에 관한 고찰" 대한비뇨기과학회 48 (48): 638-645, 2007

      2 최경수, "전립샘암 발견율에 대한 역학적 특성" 대한비뇨기과학회 50 (50): 1054-1058, 2009

      3 Crawford ED, "Understanding the epidemiology, natural history, and key pathways involved in prostate cancer" 73 : 4-10, 2009

      4 Yim SH, "Treatment and prevention of catheter- associated urinary tract infections" 4 : 159-169, 2009

      5 Berry SJ, "The development of human benign prostatic hyperplasia with age" 132 : 474-479, 1984

      6 Bratzler DW, "Surgical Infection Prevention Guideline Writers Workgroup, in the Antimicrobial prophylaxis for surgery: an advisory statement from the National Surgical Infection Prevention Project" 189 : 395-404, 2005

      7 Berry A, "Prophylactic antibiotic use in transurethral prostatic resection: a meta-analysis" 167 : 571-577, 2002

      8 Grabe M, "Perioperative antibiotic prophylaxis in urology" 11 : 81-85, 2001

      9 Matsumoto T, "Japanese guidelines for prevention of perioperative infections in urological field" 14 : 890-909, 2007

      10 Vivien A, "Infection after transurethral resection of the prostate: variation among centres and correlation with long-lasting surgical procedure" 33 : 365-369, 1998

      1 유광호, "최근 요로감염증의 주요 원인균과 항생제 감수성에 관한 고찰" 대한비뇨기과학회 48 (48): 638-645, 2007

      2 최경수, "전립샘암 발견율에 대한 역학적 특성" 대한비뇨기과학회 50 (50): 1054-1058, 2009

      3 Crawford ED, "Understanding the epidemiology, natural history, and key pathways involved in prostate cancer" 73 : 4-10, 2009

      4 Yim SH, "Treatment and prevention of catheter- associated urinary tract infections" 4 : 159-169, 2009

      5 Berry SJ, "The development of human benign prostatic hyperplasia with age" 132 : 474-479, 1984

      6 Bratzler DW, "Surgical Infection Prevention Guideline Writers Workgroup, in the Antimicrobial prophylaxis for surgery: an advisory statement from the National Surgical Infection Prevention Project" 189 : 395-404, 2005

      7 Berry A, "Prophylactic antibiotic use in transurethral prostatic resection: a meta-analysis" 167 : 571-577, 2002

      8 Grabe M, "Perioperative antibiotic prophylaxis in urology" 11 : 81-85, 2001

      9 Matsumoto T, "Japanese guidelines for prevention of perioperative infections in urological field" 14 : 890-909, 2007

      10 Vivien A, "Infection after transurethral resection of the prostate: variation among centres and correlation with long-lasting surgical procedure" 33 : 365-369, 1998

      11 Colau A, "Incidence and risk factors of bacteriuria after transurethral resection of the prostate" 39 : 272-276, 2001

      12 Sedor J, "Hospital-acquired urinary tract infections associated with the indwelling catheter" 26 : 821-828, 1999

      13 Garraway WM, "High prevalence of benign prostatic hyperthrophy in the community" 338 : 469-471, 1991

      14 Naber KG, "EAU guidelines for the management of urinary and male genital tract infections. Urinary Tract Infection (UTI) Working Group of the Health Care Office (HCO) of the European Association of Urology (EAU)" 40 : 576-588, 2001

      15 Yamamoto S, "Controversies in perioperative management and antimicrobial prophylaxis in urologic surgery" 15 : 467-471, 2008

      16 Grabe M, "Controversies in antibiotic prophylaxis in urology" 23 : 17-23, 2004

      17 Saint S, "Biofilms and catheter- associated urinary tract infections" 17 : 411-432, 2003

      18 Kim CS, "Antimicrobial prophylaxis for urologic surgery" 4 : 20-36, 2009

      19 Qiang W, "Antibiotic prophylaxis for transurethral prostatic resection in men with preoperative urinecontaining less than 100,000 bacterial per ml: a systematic review" 173 : 1175-1181, 2005

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      2016 0.07 0.07 0.06
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