장미 국내육성 품종 기내뿌리 유래 배발생캘러스의 추출물 항산화 및 피부장벽 효과 = Effect of Antioxidants and skin barrier in of embryonic callus derived the domestic rose roots

다국어 초록 (Multilingual Abstract)

In order to maintain healthy skin cells, it is most important to prevent external invasion while strengthening the skin barrier. Roses that grow the most in the country has become used in many fields as a material that has a variety of benefits. In this study, sweet yellow, which is a fragrant and bred rose in Korea, was induced with callus to confirm its potential as an eco-friendly material for skin barrier improvement. The embryogenic callus derived from the sweet yellow root was induced, and the sweet yellow callus was extracted with various solvents, and the ellagic acid was confirmed through HPLC fraction. DPPH assay was performed to determine the antioxidant of sweet yellow callus, and it was confirmed that free radical scavenging activity was activated. It was confirmed that the expression levels of the proteins filaggrin(FLG). These results lead to the conclusion that sweet yellow callus extracts have significant skin barrier effects on human keratinocytes. These results lead that sweet yellow callus extract has been proven to be an antioxidant and has a significant effect in improving the skin barrier. Therefore, it is expected that the sweet yellow callus extract can be widely used in anti-aging cosmetic materials as a fragrant rose.

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