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다국어 초록 (Multilingual Abstract)

In this study, a high sensitive giant magnetoresistance-spin valve (GMR-SV) bio-sensing device with high linearity and very low hysteresis was fabricated by photolithography and ion beam deposition sputtering system. Detection of the Fe-hemoglobin inside in a red blood and magnetic nanoparticles using the GMR-SV bio-sensing device was investigated. Here a human’s red blood includes hemoglobin, and the nanoparticles are the Co-ferrite magnetic particles coated with a shell of amorphous silica which the average size of the water-soluble bare cobalt nanoparticles was about 9 ㎚ with total size of about 50 ㎚. When 1 ㎃ sensing current was applied to the current electrode in the patterned active GMR-SV devices with areas of 5×10 ㎛² and 2×6 ㎛², the output signals of the GMRSV sensor were about 100 ㎷ and 14 ㎷, respectively. In addition, the maximum sensitivity of the fabricated GMR-SV sensor was about 0.1~0.8%/Oe. The magnitude of output voltage signals was obtained from four-probe magnetoresistive measured system, and the picture of real-time motion images was monitored by an optical microscope. Even one drop of human blood and nanopartices in distilled water were found to be enough for detecting and analyzing their signals clearly.

참고문헌 (Reference)

1 "Physics and High Technology" Korean Physical Society 12 (12): 2003

2 "Physics and High Technology" 12 (12): 2003

3 "Physics and High Technology" Korean Physical Society 12 (12): 2003

4 "J. Acd. Med. Sci. DPR Korea" 39 : 1965

5 "Anatomy and Physiology" McGraw-Hill 2004