A real-time optoelectronic device in screening of cervical intraepithelial neoplasia = A real-time optoelectronic device in screening of cervical intraepithelial neoplasia

다국어 초록 (Multilingual Abstract)

Objective: The purpose of the study was to evaluate the sensitivity and specificity of the TruScreen in the diagnosis of cervical intraepithelial neoplasia (CIN) and the benefit of an adjunct test to cervical cytology screening. Methods: Data were collected prospectively on 249 women who had undergone a loop electrosurgical excision procedure (LEEP) or hysterectomy at Kangnam St. Mary`s Hospital of Catholic University between March and December 2008. The TruScreen was performed on 249 patients and the sensitivity and specificity were determined. The accuracy of TruScreen and cervical cytology were also ascertained. Results: A remarkable improvement in the accuracy of the combined test for CIN 1 (sensitivity, 96.8%) and CIN2/3 (sensitivity, 92.4%) was noted. The sensitivity of TruScreen for CIN1 and CIN2/3 was 75.8% and 77.3%, respectively. The specificity of TruScreen for normal tissue was 85.1%. Conclusion: The present study suggests that the TruScreen is an excellent device as an adjunctive test for the detection of CIN. The instantaneous result of TruScreen in women with ASCUS or LSIL can provide rapid and reliable information.