내시경적 식도정맥류 경화요법의 효과 = The Effect of Endoscopic Injection Sclerotherapy for Variceal Eradication내시경적 식도정맥류 경화요법의 효과

다국어 초록 (Multilingual Abstract)

Esophageal variceal hemorrhage is the most life-threatening complication of portal hypertension secondary to chronic liver disease. Recently, Endoscopic Injection Sclerotherapy (EIS) has been regarded as a safe, effective method for hemostasis of acute hemorrhage and prevention of recurrent bleeding among the various treatments. Unfortunately, there is no general consensus on the EIS technique. The purpose of present study is to assess the EIS effect for variceal eradication in 184 patients with esophageal variceal hemorrhage (Urgent: 106 cases, Elective: 78 cases). All patients were classified into the 4 groups according to interval, injection site and variceal destruction. As a whole, esophageal varices were completely eradicated in 33.7%. Among the 4 groups, EIS was the most effective in patients injected at the esophagogastric junction resulting in complete variceal destruction. Esophageal stenosis, pleural effusion, fever and pain developed after EIS as minor complications. Statistically, there was no significant difference in the complication rate among the 4 groups. During the follow-up period, disappearance of cardia varix was occasionally found, regardless of complete destruction of esophageal varix. It is suggested that sclerosant should be injected at the esophagogastric junction with short intervals resulting in complete variceal destruction.