탈색모반 104예의 임상 양상 = Clinical Features of Nevus Depigmentosus in 104 Patients탈색모반 104예의 임상 양상

다국어 초록 (Multilingual Abstract)

Background：Nevus depigmentosus is known to be a congenital, stable hypomelanosis characterized by macules of varied size, of pale white color, and with discrete, regular, or occasionally serrated margins. The lesions are uniformly hypomelanotic but not amelanotic, and they show off-white accentuation with a Wood's lamp examination. It is important to differentiate nevus depigmentosus from vitiligo because both entities have different clinical courses. Objective：The purpose of this study is to investigate clinical features of nevus depigmentosus. Methods：Total 104 patients were included in this study. Data compiled were sex, age of onset, duration before visit, number of lesion, shape of lesion, and distribution of lesion. Results：In our study, there was no difference between male and female in incidence. In terms of age of onset, patients who had lesion at birth was 32.7%, below 1 year 34.6% and over 1 year 32.7%. They had variable duration before visit. Among patients, 56.7% had only one lesion, 34.6% had 2 to 5 lesions, and 2.0% of patients had more than 20 lesions. Polygonal(35.3%) or round to oval(25.9%) shape was more common than others. The trunk(41.5%) was the most common site of involvement and the neck(23.9%), face(20.1%), lower and upper extremity were involved in descending order of frequency. Conclusion：According to our study, lesions of nevus depigmentosus were found before the age of one in two thirds of patients. Almost half of patients had only one lesion. Polygonal shape was the most common shape and the trunk was the most common site in our study. These clinical features may be useful in differential diagnosis of nevus depigmentosus from other hypopigmentary disordes. (Korean J Dermatol 2000;38(5)：612~615)