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      https://www.riss.kr/link?id=A105580293

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      다국어 초록 (Multilingual Abstract)

      This paper presents an electromagnetically driven microrobot for the enhancement of mixing performance in high viscous liquid media such as blood and bone marrow. First, an electromagnetic system was fabricated, and the magnetic flux density generated from the system was compared with the theoretical value. Second, the reciprocating motion of the microrobot was demonstrated in microchannel using electromagnetic system. As a proof of concept, the mixing performance by the electromagnetically driven microrobot in high viscous liquid was investigated using safranin solution. As a result, it was completely mixed within 140 s with the reciprocating motion of the microrobot while it took 1680 s for natural diffusion. In addition, the mixing efficiency was quantitatively evaluated through a mixing index obtained by an image analysis. The proposed method provides not only wireless actuation of a microrobot with a simple design but also high mixing performance in variety of high viscous liquid media.
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      This paper presents an electromagnetically driven microrobot for the enhancement of mixing performance in high viscous liquid media such as blood and bone marrow. First, an electromagnetic system was fabricated, and the magnetic flux density generated...

      This paper presents an electromagnetically driven microrobot for the enhancement of mixing performance in high viscous liquid media such as blood and bone marrow. First, an electromagnetic system was fabricated, and the magnetic flux density generated from the system was compared with the theoretical value. Second, the reciprocating motion of the microrobot was demonstrated in microchannel using electromagnetic system. As a proof of concept, the mixing performance by the electromagnetically driven microrobot in high viscous liquid was investigated using safranin solution. As a result, it was completely mixed within 140 s with the reciprocating motion of the microrobot while it took 1680 s for natural diffusion. In addition, the mixing efficiency was quantitatively evaluated through a mixing index obtained by an image analysis. The proposed method provides not only wireless actuation of a microrobot with a simple design but also high mixing performance in variety of high viscous liquid media.

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      참고문헌 (Reference)

      1 Ferrara, K., "Ultrasound Microbubble Contrast Agents:Fundamentals and Application to Gene and Drug Delivery" 9 : 415-447, 2007

      2 Chen, B., "Research on the Kinematic Properites of a Sperm-Like Swimming Micro Robot" 7 : S123-S129, 2010

      3 Tsai, T. H., "Rapid Mixing Between Ferro-nanofluid and Water in a Semi-active Y-type Micromixer" 153 (153): 267-273, 2009

      4 Yesin, K. B., "Modeling and Control of Untethered Biomicrorobots in a Fluidic Environment Using Electromagnetic Fields" 25 (25): 527-536, 2006

      5 Wang, S., "Mixing Enhancement for High Viscous Fluids in a Microfluidic Chamber" 11 : 2081-2087, 2011

      6 Nelson, B. J., "Microrobots for Minimally Invasive Medicine" 12 : 55-85, 2010

      7 Nguyen, N.-T., "Micromixers-a Review" 15 (15): R1-R16, 2005

      8 Chen, C. Y., "Magnetically Actuated Artificial Cilia for Optimum Mixing Performance in Microfluidics" 13 : 2834-2839, 2013

      9 Sudo, S., "Magnetic Swimming Mechanism in a Viscous Liquid" 17 (17): 729-736, 2006

      10 Wang, J., "Magnetic Microrobot and Its Application in a Microfluidic System" 1 (1): 1-8, 2014

      1 Ferrara, K., "Ultrasound Microbubble Contrast Agents:Fundamentals and Application to Gene and Drug Delivery" 9 : 415-447, 2007

      2 Chen, B., "Research on the Kinematic Properites of a Sperm-Like Swimming Micro Robot" 7 : S123-S129, 2010

      3 Tsai, T. H., "Rapid Mixing Between Ferro-nanofluid and Water in a Semi-active Y-type Micromixer" 153 (153): 267-273, 2009

      4 Yesin, K. B., "Modeling and Control of Untethered Biomicrorobots in a Fluidic Environment Using Electromagnetic Fields" 25 (25): 527-536, 2006

      5 Wang, S., "Mixing Enhancement for High Viscous Fluids in a Microfluidic Chamber" 11 : 2081-2087, 2011

      6 Nelson, B. J., "Microrobots for Minimally Invasive Medicine" 12 : 55-85, 2010

      7 Nguyen, N.-T., "Micromixers-a Review" 15 (15): R1-R16, 2005

      8 Chen, C. Y., "Magnetically Actuated Artificial Cilia for Optimum Mixing Performance in Microfluidics" 13 : 2834-2839, 2013

      9 Sudo, S., "Magnetic Swimming Mechanism in a Viscous Liquid" 17 (17): 729-736, 2006

      10 Wang, J., "Magnetic Microrobot and Its Application in a Microfluidic System" 1 (1): 1-8, 2014

      11 Lee, K. Y., "Magnetic Droplet Microfluidic System Incorporated with Acoustic Excitation for Mixing Enhancement" 243 : 59-65, 2016

      12 Sahari, A., "Effect of Body Shape on the Motile Behavior of Bacteria-Powered Swimming Microrobot (BacteriaBots)" 14 : 999-1007, 2012

      13 Zhou, Y., "Dynamic Trapping and Two-dimensional Transport of Swimming Microorganisms Using a Rotating Magnetic Microrobot" 14 : 2177-2182, 2014

      14 Allen, T. M., "Drug Delivery Systems: Entering the Mainstream" 303 (303): 1818-1822, 2004

      15 Zhang, L., "Characterizing the Swimming Properties of Artificial Bacterial Flagella" 9 (9): 3663-3667, 2009

      16 Nichols, M., "Cardiovascular Disease in Europe 2014: Epidemiological Update" 35 (35): 2950-2959, 2014

      17 Saito, S., "Angioplasty for Chronic Total Occlusion by Using Tapered-tip Guidewires" 59 (59): 305-311, 2003

      18 Mensing, G. A., "An Externally Driven Magnetic Microstirrer" 362 (362): 1059-1068, 2004

      19 Zhang, Y., "Advanced Materials and Processing for Drug Delivery: the Past and the Future" 65 (65): 104-120, 2013

      20 Khatavkar, V. V., "Active Micromixer Based on Artificial Cilia" 19 (19): 083605-1-083605-13, 2007

      21 Niu, X., "Active Microfluidic Mixer Chip" 88 (88): 153508-, 2006

      22 Ghanbari, A., "A Novel Swimming Microrobot Based on Artificial Cillia for Biomedical Applications" 63 (63): 399-416, 2011

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      2023 평가예정 재인증평가 신청대상 (재인증)
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      2010-01-01 평가 등재후보 1차 FAIL (등재후보1차) KCI등재후보
      2009-01-01 평가 등재후보학술지 유지 (등재후보1차) KCI등재후보
      2008-01-01 평가 등재후보학술지 유지 (등재후보1차) KCI등재후보
      2006-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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