Management of malignant central airway obstruction in a tertiary hospital in viet nam = Management of malignant central airway obstruction in a tertiary hospital in viet nam

다국어 초록 (Multilingual Abstract)

Objective: To evaluate the causes and treatments of patients with malignant central airway obstruction (CAO). Subjects: 37 patients were diagnosed with malignant CAO at Respiratory Center of Bach Mai Hospital. Methods: Retrospective and Prospective, descriptive study. Results: Average age was 53.8 ± 13.1 years. CAO occurred mainly in the 45-59 age group and in men more than women. No significant differences between the number of patients with cancer originated from in (group 1) and out (group 2) of the airway with regard to the number of patients, degree of stenosis and location of stenosis. In group 1, NSCLC accounted for the majority. In group 2, squamous-cell esophageal carcinoma had the highest proportion. The prevalence of patient having treatment was higher than not having treatment statistically. In the treatment group, the number of participants undergoing a combination of airway stent insertion and balloon dilatation was predominant. There were no significant differences in causes or locations or degrees of stenosis respecting treatment modalities. Participants having comfort after treatment accounted for the majority. In no treatment group and treatment group, cumulative proportions surviving were 0% (at 11th month) and 44.3% (at 9th month), respectively. The survival time in the treatment group (15.1 ± 3.4 months) was statistically longer than in no treatment group (4.4 ± 1.9 months) (p = 0.031). Conclusions: Causes of malignant CAO are varied and induce a variety of location and degree of stenosis, thereby leading to diverse treatments. Clinicians need to consider having appropriate treatments for patients to increase their comfort and survival time.