Sevoflurane 마취 후 발생한 급성 간 기능 장애 = Acute liver injury after sevoflurane anesthesia

다국어 초록 (Multilingual Abstract)

Halothane, isoflurane and desflurane are metabolized to hepatotoxic trifluoroacetyl proteins. But sevoflurane is metabolized to hexafluoroisopropanol. Hexafluoroisopropanol has a low binding affinity for liver protein and is therefore rapidly converted to glucuronidate that are excreted in the urine. Thus sevoflurane has been considered to have a very low potential for hepatotoxicity. We report a case of a 67 years old woman who developed acute hepatic dysfunction after sevoflurane anesthesia.

참고문헌 (Reference)

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