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      Impact of the ketogenic diet on body fat, muscle mass, and exercise performance: a review

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      https://www.riss.kr/link?id=A108918494

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      다국어 초록 (Multilingual Abstract)

      [Purpose] The purpose of this review was to investigate the effects of the ketogenic diet (KD), on body fat, muscle mass, and exercise performance. As the KD is a subject of ongoing debate, we also present the existing evidence regarding its potential benefits in the aforementioned areas of body fat, muscle mass, and exercise performance.
      [Methods] A literature search was conducted using the keywords “ketogenic diet, low-carbohydrate diet, high-fat diet, body fat, muscle mass, and exercise performance” in PubMed, Web of Science, and Google Scholar.
      [Results] The KD effectively reduced body fat in the short term and, preserved muscle mass during weight loss, however, its impact on exercise performance remains inconclusive owing to various factors.
      [Conclusion] While controversial, it is undeniable that the KD has the potential to affect body fat, muscle mass, and exercise performance. Consequently, additional research is required to elucidate the underlying mechanisms across various populations, optimize their implementation, and understand their long-term effects.
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      [Purpose] The purpose of this review was to investigate the effects of the ketogenic diet (KD), on body fat, muscle mass, and exercise performance. As the KD is a subject of ongoing debate, we also present the existing evidence regarding its potential...

      [Purpose] The purpose of this review was to investigate the effects of the ketogenic diet (KD), on body fat, muscle mass, and exercise performance. As the KD is a subject of ongoing debate, we also present the existing evidence regarding its potential benefits in the aforementioned areas of body fat, muscle mass, and exercise performance.
      [Methods] A literature search was conducted using the keywords “ketogenic diet, low-carbohydrate diet, high-fat diet, body fat, muscle mass, and exercise performance” in PubMed, Web of Science, and Google Scholar.
      [Results] The KD effectively reduced body fat in the short term and, preserved muscle mass during weight loss, however, its impact on exercise performance remains inconclusive owing to various factors.
      [Conclusion] While controversial, it is undeniable that the KD has the potential to affect body fat, muscle mass, and exercise performance. Consequently, additional research is required to elucidate the underlying mechanisms across various populations, optimize their implementation, and understand their long-term effects.

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      참고문헌 (Reference)

      1 Newman JC, "β-hydroxybutyrate : a signaling metabolite" 37 : 51-76, 2017

      2 Badman MK, "Very low carbohydrate ketogenic diet improves glucose tolerance in ob/ob mice independently of weight loss" 297 : E1197-204, 2009

      3 Gillen JB, "Twelve weeks of sprint interval training improves indices of cardiometabolic health similar to traditional endurance training despite a five-fold lower exercise volume and time commitment" 11 : e0154075-, 2016

      4 Nymo S, "Timeline of changes in appetite during weight loss with a ketogenic diet" 41 : 1224-1231, 2017

      5 Kephart WC, "The three-month effects of a ketogenic diet on body composition, blood parameters, and performance metrics in crossfit trainees : a pilot study" 6 : 1-, 2018

      6 Maalouf M, "The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies" 59 : 293-315, 2009

      7 Youm YH, "The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease" 21 : 263-269, 2015

      8 Paoli A, "The ketogenic diet and sport : a possible marriage?" 43 : 153-162, 2015

      9 Ramos JS, "The impact of high-intensity interval training versus moderate-intensity continuous training on vascular function : a systematic review and meta-analysis" 45 : 679-692, 2015

      10 Maffetone PB, "Revisiting the global overfat pandemic" 8 : 51-, 2020

      1 Newman JC, "β-hydroxybutyrate : a signaling metabolite" 37 : 51-76, 2017

      2 Badman MK, "Very low carbohydrate ketogenic diet improves glucose tolerance in ob/ob mice independently of weight loss" 297 : E1197-204, 2009

      3 Gillen JB, "Twelve weeks of sprint interval training improves indices of cardiometabolic health similar to traditional endurance training despite a five-fold lower exercise volume and time commitment" 11 : e0154075-, 2016

      4 Nymo S, "Timeline of changes in appetite during weight loss with a ketogenic diet" 41 : 1224-1231, 2017

      5 Kephart WC, "The three-month effects of a ketogenic diet on body composition, blood parameters, and performance metrics in crossfit trainees : a pilot study" 6 : 1-, 2018

      6 Maalouf M, "The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies" 59 : 293-315, 2009

      7 Youm YH, "The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease" 21 : 263-269, 2015

      8 Paoli A, "The ketogenic diet and sport : a possible marriage?" 43 : 153-162, 2015

      9 Ramos JS, "The impact of high-intensity interval training versus moderate-intensity continuous training on vascular function : a systematic review and meta-analysis" 45 : 679-692, 2015

      10 Maffetone PB, "Revisiting the global overfat pandemic" 8 : 51-, 2020

      11 Poplawski MM, "Reversal of diabetic nephropathy by a ketogenic diet" 6 : e18604-, 2011

      12 Hall KD, "Quantification of the effect of energy imbalance on bodyweight" 378 : 826-837, 2011

      13 Iraki J, "Nutrition recommendations for bodybuilders in the off-season : a narrative review" 7 : 154-, 2019

      14 Gasior M, "Neuroprotective and disease-modifying effects of the ketogenic diet" 17 : 431-439, 2006

      15 Partsalaki I, "Metabolic impact of a ketogenic diet compared to a hypocaloric diet in obese children and adolescents" 25 : 697-704, 2012

      16 Volek JS, "Metabolic characteristics of keto-adapted ultra-endurance runners" 65 : 100-110, 2016

      17 Tisdale MJ, "Mechanisms of cancer cachexia" 89 : 381-410, 2009

      18 Lambert CP, "Macronutrient considerations for the sport of bodybuilding" 34 : 317-327, 2004

      19 Noto H, "Low-carbohydrate diets and all-cause mortality : a systematic review and meta-analysis of observational studies" 8 : e55030-, 2013

      20 Burke LM, "Low carbohydrate, high fat diet impairs exercise economy and negates the performance benefit from intensified training in elite race walkers" 595 : 2785-2807, 2017

      21 Paoli A, "Long term successful weight loss with a combination biphasic ketogenic mediterranean diet and mediterranean diet maintenance protocol" 5 : 5205-5217, 2013

      22 Sumithran P, "Ketosis and appetite-mediating nutrients and hormones after weight loss" 67 : 759-764, 2013

      23 Pathak SJ, "Ketogenic diets and mitochondrial function : benefits for aging but not for athletes" 51 : 27-33, 2023

      24 Streijger F, "Ketogenic diet improves forelimb motor function after spinal cord injury in rodents" 8 : e78765-, 2013

      25 Paoli A, "Ketogenic diet for obesity : friend or foe?" 11 : 2092-2107, 2014

      26 Paoli A, "Ketogenic diet does not affect strength performance in elite artistic gymnasts" 9 : 34-, 2012

      27 Paoli A, "Ketogenic diet and microbiota : friends or enemies?" 10 : 534-, 2019

      28 McSwiney FT, "Keto-adaptation enhances exercise performance and body composition responses to training in endurance athletes" 83 : e1-2, 2018

      29 Slater GJ, "Is an energy surplus required to maximize skeletal muscle hypertrophy associated with resistance training" 6 : 131-, 2019

      30 Cahill GF, "Fuel metabolism in starvation" 26 : 1-22, 2006

      31 Tinsley GM, "Fat-free mass changes during ketogenic diets and the potential role of resistance training" 26 : 78-92, 2016

      32 Goss AM, "Effects of weight loss during a very low carbohydrate diet on specific adipose tissue depots and insulin sensitivity in older adults with obesity : a randomized clinical trial" 17 : 64-, 2020

      33 Paoli A, "Effects of two months of very low carbohydrate ketogenic diet on body composition, muscle strength, muscle area, and blood parameters in competitive natural body builders" 13 : 374-, 2021

      34 Vargas-Molina S, "Effects of the ketogenic diet on muscle hypertrophy in resistance-trained men and women : a systematic review and meta-analysis" 19 : 12629-, 2022

      35 Wilson JM, "Effects of ketogenic dieting on body composition, strength, power, and hormonal profiles in resistance training men" 34 : 3463-3474, 2020

      36 Sawyer BJ, "Effects of high-intensity interval training and moderate-intensity continuous training on endothelial function and cardiometabolic risk markers in obese adults" 121 : 279-288, 2016

      37 Cipryan L, "Effects of a very low-carbohydrate high-fat diet and high-intensity interval training on visceral fat deposition and cardiorespiratory fitness in overfat individuals : a randomized controlled clinical trial" 8 : 785694-, 2021

      38 Sawyer JC, "Effects of a short-term carbohydrate-restricted diet on strength and power performance" 27 : 2255-2262, 2013

      39 Sondike SB, "Effects of a low-carbohydrate diet on weight loss and cardiovascular risk factor in overweight adolescents" 142 : 253-258, 2003

      40 Hussain TA, "Effect of low-calorie versus low-carbohydrate ketogenic diet in type 2 diabetes" 28 : 1016-1021, 2012

      41 Shaw DM, "Effect of a ketogenic diet on submaximal exercise capacity and efficiency in runners" 51 : 2135-2146, 2019

      42 Ludwig DS, "Do lower-carbohydrate diets increase total energy expenditure? An updated and reanalyzed meta-analysis of 29 controlled-feeding studies" 151 : 482-490, 2021

      43 Gibson AA, "Do ketogenic diets really suppress appetite? A systematic review and meta-analysis" 16 : 64-76, 2015

      44 Sackner-Bernstein J, "Dietary intervention for overweight and obese adults : comparison of low-carbohydrate and low-fat diets. A meta-analysis" 10 : e0139817-, 2015

      45 Bisschop PH, "Dietary fat content alters insulin-mediated glucose metabolism in healthy men" 73 : 554-559, 2001

      46 Bostock ECS, "Consumer reports of"keto flu"associated with the ketogenic diet" 7 : 20-, 2020

      47 Janda M, "An instrument to measure adherence to weight loss programs : the compliance praxis survey-diet(COMPASS-diet)" 5 : 3828-3838, 2013

      48 Yancy WS Jr, "A low-carbohydrate, ketogenic diet versus a low-fat diet to treat obesity and hyperlipidemia : a randomized, controlled trial" 140 : 769-777, 2004

      49 Greene DA, "A low-carbohydrate ketogenic diet reduces body weight without compromising performance in powerlifting and olympic weightlifting athletes" 32 : 3373-3382, 2018

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