Complete genome sequence of Granulicatella adiacens KHUD_009 isolated from subgingival biofilm

다국어 초록 (Multilingual Abstract)

Granulicatella adiacens is known to participate in several oral diseases including periodontitis, caries and endodontic infection. However, complete reference genome sequences for G. adiacens have only been analyzed for non-oral isolates. We sequenced the complete genome of G. adiacens KHUD_009 originated from the subgingival biofilm of a Korean with periodontitis, using the PacBio Sequel II platform. The genome is 1,949,834 bp with a GC content of 37.81% and includes 1,830 protein-coding genes, 15 rRNAs, and 58 tRNA. We identified that KHUD_009 carries several genes encoding virulence-associated proteins such as phosphocarrier and acyl carrier proteins and type VII secretion proteins.

참고문헌 (Reference)

1 Collins MD, "The genus Abiotrophia (Kawamura et al.) is not monophyletic: proposal of Granulicatella gen. nov., Granulicatella adiacens comb. nov., Granulicatella elegans comb. nov. and Granulicatella balaenopterae comb. nov" 50 : 365-369, 2000

2 Karched M, "Proteomic analysis and virulence assessment of Granulicatella adiacens secretome" 9 : 104-, 2019

3 Ruoff KL, "Nutritionally variant streptococci" 4 : 184-190, 1991

4 Lin CH, "Infective endocarditis caused by nutritionally variant streptococci" 334 : 235-239, 2007

5 서미령 ; 박윤수 ; 김의주 ; 이헌남 ; 오경용 ; 서일혜 ; 최창휴, "Granulicatella adiacens 심내막염 1예" 대한감염학회 42 (42): 311-314, 2010

6 Gupta S, "Granulicatella adiacens abscess : two rare cases and review" 10 : 121-123, 2018

7 Spencer BL, "Evolving understanding of the type VII secretion system in Gram-positive bacteria" 18 : e1010680-, 2022

8 Belstrøm D, "Differences in bacterial saliva profile between periodontitis patients and a control cohort" 41 : 104-112, 2014

9 Kanasi E, "Clonal analysis of the microbiota of severe early childhood caries" 44 : 485-497, 2010

10 Siqueira JF. Jr, "Catonella morbi and Granulicatella adiacens: new species in endodontic infections" 102 : 259-264, 2006