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      동물 실험을 통한 Aspirin과 Ibuprofen의 소염 및 진통 작용의 비교 = A comparative study of Aspirin and Ibuprofen on their antiinflammatory effects in rats, and their analgesic effects inmice

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      https://www.riss.kr/link?id=A30050510

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      A Comparative study of Aspirin and Ibuprofen on their antiinflammatory and analgesic effect were examined by using rats and mice respectively.
      The results obtained are summarized as follows:
      1. The edema of left hind paw produced by injection of yeast solution was decreased significantly in the rats treated by 300mg/kg of Aspirin and 54mg/kg of Ibuprofen as compared with that of control group.
      But no significant difference in the size of edema was observed between the Aspirin and the Ibuprofen treated group.
      2. The numbers of abdominal contraction in the mice treated with Aspirin 120mg/kg, Aspirin 240mg/kg, Ibuprofen 7.5mg/kg, and Ibuprofen 10mg/kg were decreased significantly compared with that of control group.
      But no significant difference in the numbers of abdominal contraction was observed between the Aspirin and the Ibuprofen treated group.
      By the above results, it is concluded that Ibuprofen is more potent than Aspirin but possesses almost same efficacies in its antiinflammatory and analgesic effect in all dosages used in this experiment.
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      A Comparative study of Aspirin and Ibuprofen on their antiinflammatory and analgesic effect were examined by using rats and mice respectively. The results obtained are summarized as follows: 1. The edema of left hind paw produced by injection of yea...

      A Comparative study of Aspirin and Ibuprofen on their antiinflammatory and analgesic effect were examined by using rats and mice respectively.
      The results obtained are summarized as follows:
      1. The edema of left hind paw produced by injection of yeast solution was decreased significantly in the rats treated by 300mg/kg of Aspirin and 54mg/kg of Ibuprofen as compared with that of control group.
      But no significant difference in the size of edema was observed between the Aspirin and the Ibuprofen treated group.
      2. The numbers of abdominal contraction in the mice treated with Aspirin 120mg/kg, Aspirin 240mg/kg, Ibuprofen 7.5mg/kg, and Ibuprofen 10mg/kg were decreased significantly compared with that of control group.
      But no significant difference in the numbers of abdominal contraction was observed between the Aspirin and the Ibuprofen treated group.
      By the above results, it is concluded that Ibuprofen is more potent than Aspirin but possesses almost same efficacies in its antiinflammatory and analgesic effect in all dosages used in this experiment.

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