A randomized study was performed to compare the effect of clotrimazole troches and ketoconazole in the treatment of oral moniliasis. Eight patients who were treated with clotrimazole troches (10 mg 5 times a day for fourteen days) showed a resolution ...
A randomized study was performed to compare the effect of clotrimazole troches and ketoconazole in the treatment of oral moniliasis. Eight patients who were treated with clotrimazole troches (10 mg 5 times a day for fourteen days) showed a resolution of symptoms and signs in 1.4 days after treatment initially and 3.0 days after treatment completely. In six cases with ketoconazole therapy (400 mg once a day p.o. for fourteen days), initial and complete clinical response were observed in 1.7 days and 5.0 days after treatment. No side effect was found in patients with clotrimazole troches group, while mild degree of nausea, anorexia and epigastric discomfort were developed in patients with ketoconazole group. These findings suggest clotrimazole troche is as effective as ketoconazole for oral moniliasis and more tolerable than latter.