한국남성(韓國男性)의 심혈관질환(心血管疾患)으로 인한 사망관련요인연구(死亡關聯要因硏究) 고혈압성질환(高血壓性疾患)을 중심(中心)으로 = A Case-Control Study on Risk Factors for the Major Cardiovascular Deaths in Korean Men: Hypertensive Disease and Cerebrovascular Disease

다국어 초록 (Multilingual Abstract)

By means of case-control study, various hypothesized risk factors for cardiovascular diseases were evaluated in the Korean men. Cases are 455 men who died at age 35-65 between October 1982 and September 1983 with an underlying cause of death, as reported on the death certificate, of hypertensive disease (N=95. ICD 401-405) or non-traumatic cerebrovascular diseae (N=360. ICD 430-438). Each case was matched on age and wife`s parity to a living male from the same neighborhood. Wives of cases and controls were interviewed at home as surrogates.
Major findings obtained from this study are as follows:
1) In comparison of personal characteristics between cases and controls, education, occupation and religion appeared to be significantly different: cases were more likely to have received higher education, to be Christian, and to have had administrative or managerial jobs.
2) In univariate analysis of the associaton of hypothesized risk factors and cardiovascular deaths, frequent alcohol drinking, meat diet, obesity, histories of hypertension, diabetes and heart disase, and the history of one or both parents CVD death were found to be significant risk factors.
3) Multivariate logistic regression analysis of risk factors including personal characteristics variables that were significantly different between cases and controls revealed that higher education, frequent alcohol drinking, lack of physical exercise, obesity and history of hypertension were significantly related to the cardiovascular deaths. History of hypertension was strongest risk factor and the adjusted odds ratios was 7.69 (95% C.I.=5.21-12.15). For hypertensive disease deaths, only histories of hypertension and heart disease were found to be significant, and for cerebrovascular deaths, lack of physical exercise, obesity and history of hypertension were significant risk factors.
4) Cardiovascular death risk for Korean men was not associated with cigarette smoking, diet, coffee drinking and history of parents CVD deaths.
In conclusion, this study emphasizes the importance of control measures of hypertension and the related factors such as obesity, lack of physical exercise, alcohol drinking and so on to decrease current high cardiovascular mortality, especially cerebrovascular disease deaths among Korean men.