조기 위암에서 림프절 전이와 위벽침윤도에 영향을 미치는 인자 = Parameters Influencing Lymph Node Metastasis and Depth of Invasion in Early Gastric Cancer조기 위암에서 림프절 전이와 위벽침윤도에 영향을 미치는 인자

다국어 초록 (Multilingual Abstract)

Background/Aims: In general, the prognosis of early gastric cancer is excellent. But in case of lymph node metastasis, the survival rate is significantly poorer than ca.es without lymph n<xte metastasis. Submucosal lesion is known to be important factors related to lymph node metastasis and prognosis. The purpose of this study is to identify the clinica] parameters which are related to these two prognostic factors. Methods: From January ]990 to March 1993, 230 cases(29.6%) of early gastric cancer among 776 cases of gastric cancer were operated at the Asan Medical Center. The average age of the patients was 53 and 74 cases(32.2%) were over 60 years of' age. Male to female ratio was 2.3:l. Distal third was the most frequent 1ocation followed by middle and upper third. Multiple lesions were found in 18 cases(7.8%). The mean of' long diameter was 2.87cm and long diameter was lrger than 3cm in 99 cases(43.1%). Results: The are of lesion was le.s than 2cm in 78 cases(33.9%). Macroscopically protruded lesions were 31 cases(13.S/o) and type llc were 139 cases(60.9%). Of all, 31 cases(l3.5%) had lymph node metastasis and 116 cases(50.4%I) were mucosal lesion. 109 cases(47.4%) were poorly differentiated adenocarcinoma histologically. Diffuse, intestinal and mixed type according to Lauren classification were 98 cases(44.9%), 98 cases (44.9%) and 22 cases(2.2%) and 21 cases(9.l lo) respectively. The parameters influencing lymph node metastasis were depth of invasion, tumor size(long diameter), tumor area, Lauren classification, lymphatic and vascular invasion. The age of the patient, tumor size(long diameter), tumor area, lymphatic and vascular invasion were related to the depth of invasion. Conclusion: The number of positive lymph node correlated to the depth of invasion. (Korean J Gastroenterol 1995;27:174 - 182).