Background and Objectives:There are considerable geographic and ethnic diferences in the incidence, age distribution, and hi-stologic subtypes of lymphoma. There are diferences in outcomes of treatment and prognosis according to the stage, age, prim...
Background and Objectives:There are considerable geographic and ethnic diferences in the incidence, age distribution, and hi-stologic subtypes of lymphoma. There are diferences in outcomes of treatment and prognosis according to the stage, age, primary site, serum LDH, and performance status. We performed this study to investigate the outcomes of treatment, prognostic factors, and differences between Hodgkins disease (HD) and non-Hodgkins lymphoma (NHL). Materials and Method:A retrospec-tive review was made of 84 malignant lymphoma patients involving the head and neck treated between 1993 and 2000 with che-motherapy or combined modality therapy at Hanyang University Hospital. Results:Among 84 patients included in the study, 68 had NHL and 16 had HD. The median age of patients at diagnosis was 55 and 43 for patients of NHL and HD, respectively. Male patients made up 56% of the NHL patients and 75% of the HD patients. The most comon extranodal site of NHL was palatine tonsil (16.2%) (64.7%) in NHL and mixed cellu-larity (43.8%) in HD. The useful prognostic factors predicting overall survival were stage, histologic subtype, serum LDH, and performance status for NHL, and age for HD. Conclusion:Although the characteristics of malignant lymphoma in Korea diffe-red from those in the western countries, International Prognostic Index (IPI) still proved useful. (Korean J Otolaryngol 2003 ; 46 :324-30)