漢方製劑의 行動藥理學的 硏究 (第5報) : 柏子仁의 中樞抑制作用에 關하여 Central Depressive Action of Thujae Semen = Studies on Behavioral Pharmacology of Oriental Drug Preparation(Ⅴ)

다국어 초록 (Multilingual Abstract)

The behavioral effects of Thujae semen aqueous extracts which is used to insomnia, neuroses, nervous prostration in oriental medicine were compared with those of chlorpromazine and dizaepam as a comparison drug in mouse and rat.
Effects of Thujae semen aqueous extracts on the central nervous depressive action were tested by spontaneous movement activity using photoelectrical method, smoked paper method and open field method, sloped plate method, extension of hypnosis time induced with phenobarbital-Na pentobarbital-Na and defense against convulsive action induced with picrotoxin, strychnine and electroshock.
Thujae semen aqueous extracts was found to pharmacologically expect above various action similar to those of chlorpromazine Hcl and diazepam but action of sample was weaker than that of chlorpromazine and diazepam.