12주 유산소성 운동이 고령여성의 염증반응인자와 항염증반응인자에 미치는 영향 = Effects of Aerobic Exercise on Inflammatory Factors and Anti-inflammatory Factors in Elderly Women

다국어 초록 (Multilingual Abstract)

The purpose of this study was to verify the effect of 12weeks aerobic exercise on inflammatory factors(high sensitivity C-reactive protein; hs-CRP, Erythrocyte Sedimentation Rate; ESR, white blood cell; WBC, Fibrinogen) and anti-inflammatory factors(Adiponectin, tissue plasminogen activator; t-PA) in elderly women. The subjects were divided into two groups; exercise group(n=12), control group(n=12). In exercise group, line dance were performed 60minutes a day, 3 times a week during the 12weeks program. The results were as follows;
First, in the exercise group, significant decreased on hs-CRP and fibrinogen after the training, also, significant difference found on hs-CRP compared to that of control group, however, tendency of decreased ESR and WBC showed but no significant differences on it. Second, there are significant increased on adiponectin in exercise groups, and it increased compared to that of control group. However, no significant changes on t-PA.
Consequently, aerobic exercise was effect on improvement of both inflammatory factors and anti-inflammatory factors, so that it can be reduce the Coronary Artery Disease(CAD)-related risk in elderly women.

목차 (Table of Contents)

• Abstract
• Ⅰ. 서론
• Ⅱ. 연구방법
• Ⅲ. 결과
• Ⅳ. 논의
• Ⅴ. 결론
• 참고문헌

참고문헌 (Reference)

1 변재철, "점진적 최대부하운동이 혈중 급성염증인자와 섬유소 용해능에 미치는 영향" 한국체육학회 43 (43): 429-440, 2004

2 류호상, "유산소 트레이닝이 비만남성의 Axute Inflammatory Markers, t-PA 및 Cholesterol 농도에 미치는 영향" 한국체육학회 44 (44): 325-335, 2005

3 Booth, F. W., "Waging war on modern chronic disease: primary prevention through exercise biology" 88 (88): 774-787, 2000

4 Christos, K., "The effects of physical activity on serum C-reactive protein and inflammatoty markers" 45 (45): 1563-1569, 2005

5 Petersen, A. M., "The anti-inflammatory effect of exercise" 98 (98): 1154-1162, 2005

6 Korean National Statistical Office, "The Cause Death of Statistics 2007(Deaths And Death Rates)" 2008

7 Pedersen, B. K., "Searching for the exercise factor: is IL-6 a candidate?" 24 (24): 113-119, 2003

8 Abramson, J. L., "Relationship between physical activity and inflammation among apparently healthy middle-aged and older US adults" 162 (162): 1286-1292, 2002

9 Mattusch, F., "Reduction of the plasma concentration of C-reactive protein following nine months of endurance training" 21 (21): 21-24, 1999

10 Goldstein, L. B., "Primary prevention of ischemic stroke: A statement for healthcare professionals from the Stroke Council of the American Heart Association" 32 : 2575-2579, 2001

11 Neuberger, G. B., "Predictors of exercise and effects of exercise on symptoms, function, aerobic fitness, and disease outcomes of rheumatoid arthritis" 57 (57): 943-952, 2007

12 Yano, K., "Plasma fibrinogen as a predictor of total and cause-specific mortality in elderly Japanese-American men" 21 (21): 1065-1070, 2001

13 Isasi, C. R., "Physical fitness and C-reactive protein level in children and young adults: the Columbia University BioMarkers Study" 111 (111): 332-338, 2003

14 MacAuley, D., "Physical activity, physical fitness, blood pressure, and fibrinogen in the Northern Ireland health and activity survey" 50 (50): 258-263, 1996

15 Folsom, A. R, "Physical activity and incidence of coronary heart disease in middle-aged women and men" 29 : 901-909, 1997

16 King, D. E., "Inflammatory markers and exercise: differences related to exercise type" 35 (35): 575-581, 2003

17 Pruitt, B. E., "Health style; Decisions for living well(2nd, ed)" Alayn and Bacon 1999

18 Szymanski, L. M, "Fibrinolytic responses to moderate intensity exercise. Comparison of physically active and inactive men" 14 (14): 1746-1750, 1994

19 Marcell, T. J., "Exercise training is not associated with improved levels of C-reactive protein or adiponectin" 54 : 533-541, 2005

20 Gaspardone, A., "Exercise induced myocardial ischaemia does not cause increase in C-reactive protein concentration" 84 : 668-669, 2000

21 Natali A., "Erythrocyte sedimentation rate, coronary atherosclerosis, and cardiac mortality" 24 (24): 639-648, 2003

22 Gillum, R. F., "Erythrocyte sedimentation rate and stroke incidence in the NHANES I Epidemiologic Follow-up Study" 28 (28): 873-874, 1997

23 Gillum, R. F., "Erythrocyte sedimentation rate and coronary heart disease: the NHANES I Epidemiologic Follow-up Study" 48 (48): 353-361, 1995

24 Simpson, K. A., "Effects of exercise on adiponectin: a systematic review" 16 (16): 241-256, 2008

25 Smith, D. T., "Effects of ageing and regular aerobic exercise on endothelial fibrinolytic capacity in humans" 546 (546): 289-298, 2003

26 Esposito, K., "Effect of weight liss and lifestyle changes on vascular inflammatory markers in obese women: a randomizes trial" 289 : 1799-1804, 2003

27 Albert, M. A., "Effect of physical activity on serum C-reactive protein" 93 : 221-225, 2004

28 Matsubara, M., "Decreased plasma adiponectin concentrations in women with dyslipidemia" 87 (87): 2764-2769, 2002

29 Febbraio, M. A., "Contraction-induced myokine production and release: is skeletal muscle an endocrine organ?" 33 (33): 114-119, 2005

30 Geffken, D. F., "Association between physical activity and markers of inflammation in a healthy elderly population" 153 (153): 242-250, 2001

31 Stefan, E, "Association between adiponectin and mediators of inflammation in obese women" 52 : 942-947, 2003

32 Reinehr, T., "Adiponectin before and after weight loss in obese children" 89 : 3790-3794, 2004

33 Gabay, C., "Acute-phase proteins and other systemic responses to inflammation" 29 : 1376-, 1999

34 Berlin, J. A, "A meta-analysis of physical activity in the prevention of coronary heart disease" 132 : 612-628, 1992