기능장애성 자궁출혈의 임상 및 병리학적 고찰 = Clinical and Pathology Study of Dysfunctional Uterine Bleeding

다국어 초록 (Multilingual Abstract)

Dysfunctional uterine bleeding is defined as bleeding from the uterine endometrium unrelated to anatomic lesions of the uterus. According to definition, the diagnosis of dysfunctional uterine bleeding seems to be a diagnosis of exclusion. Dysfunctional uterine bleeding is the most frequent problem of all gynecologic disease and occurs more frequently during puberty and in the perimenopausal period and is less common during the reproductive period. Pathologically, the endometrium of DUB patients represents the proliferative pattern most commonly. We performed the clinical and pathologic studies of DUB patients in order to evaluate the abnormal uterine bleeding and brief review of literature was made. 113 cases of dysfunctional uterine bleeding obtained by endometrial biopsy. The results were follows: 1. Age distribution of uterine bleeding was mainly 5th decade. 2. Dysfunctional uterine bleeding patients were mainly multigravidas and showed 5 ~ 6 times of pregnancy and 2 ~ 3 times of pregnancy. 3. Among variable bleeding patterns, menorrhagia with intermenstrual bleeding was the most common pattern. 4. The histologic findings of endometrium were proliferative phase, secretory phase, hyperplasia irregular shedding, atrophic endometrium in order of frequency. 5. According to endometrial biopsy, the incidence of anovulatory DUB was 67 % (46 cases out of 66 cases) and ovulatory DUB was 33 % (20 cases out of 66 cases).