Novel Molecules Regulating Energy Homeostasis: Physiology and Regulation by Macronutrient Intake and Weight Loss

다국어 초록 (Multilingual Abstract)

Excess energy intake, without a compensatory increase of energy expenditure, leads to obesity. Several molecules are involved inenergy homeostasis regulation and new ones are being discovered constantly. Appetite regulating hormones such as ghrelin, peptidetyrosine-tyrosine and amylin or incretins such as the gastric inhibitory polypeptide have been studied extensively while othermolecules such as fibroblast growth factor 21, chemerin, irisin, secreted frizzle-related protein-4, total bile acids, and heme oxygenase-1 have been linked to energy homeostasis regulation more recently and the specific role of each one of them has not beenfully elucidated. This mini review focuses on the above mentioned molecules and discusses them in relation to their regulation bythe macronutrient composition of the diet as well as diet-induced weight loss.

참고문헌 (Reference)

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