미만성 간질성 폐질환의 종류와 진단적 접근방법|RISS 상세보기

다국어 초록 (Multilingual Abstract)

Diffuse interstitial lung diseases (DILDs) are a heterogeneous group of non-neoplastic, noninfectious

disorders resulting from damage to the lung parenchyma, and present with similar

clinical features. There has been difficulty in the classification and diagnosis of DILDs because

they contain more than 200 diseases. The American Thoracic Society and European Respiratory

Society (ATS/ERS) expert meeting have proposed to classify DILDs into 4 categories, ① known

cases, ② granulomatous diseases, ③ idiopathic interstitial pneumonias (IIPs), and ④ other

forms. Among them, IIPs also comprise several different clinicopathological entities; however, it

was previously thought to be a single disease, idiopathic pulmonary fibrosis (IPF), and resulted in

a lot of confusion. Therefore, the ATS/ERS consensus classification provided a standardized

nomenclature and diagnostic criteria of IIPs. IIPs are now classified into seven clinicopathologic

entities; IPF, nonspecific interstitial pneumonia (NSIP), cryptogenic organizing pneumonia

(COP), acute interstitial pneumonia (AIP), respiratory bronchiolitis-associated interstitial lung

disease (RB-ILD), desquamative interstitial pneumonia (DIP), and lymphoid interstitial

pneumonia (LIP). Because of these complexities, it is not easy to make the diagnosis of the

patients with DILDs. This review will present a brief overview of DILDs and summary of

diagnostic approaches with highlights on several specific items. An important thing to emphasize

is the diagnosis of DILDs should be multi-disciplinary and the final diagnosis should be rendered

only after reviewing all of the clinical, radiological, and pathological data of the patient. The more

detailed description and discussion on some common diseases of DILDs will be followed by

different authors.

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