Background: We aimed to explore the recent 11 years (2002-2012) incidence trends of chronic hepatitis B (CHB), chronic hepatitis C (CHC), liver cirrhosis (LC) and primary liver cancer (PLC, subcategories: hepatocellular carcinoma, intrahepatic bile du...
Background: We aimed to explore the recent 11 years (2002-2012) incidence trends of chronic hepatitis B (CHB), chronic hepatitis C (CHC), liver cirrhosis (LC) and primary liver cancer (PLC, subcategories: hepatocellular carcinoma, intrahepatic bile duct and unspecifi ed liver tumors) and mortality trend of PLC in Korea.Methods: We analyzed trends of incidence rates (the number of patients divided by total population covered by health insurance service) per 100,000 by age and sex for the recent 11 years in CHB, CHC, LC and PLC from the data of National Health Insurance Service (NHIS). We also analyzed trend of mortality rates caused by PLC per 100,000 by sex for the recent 11 years from the data of Korean Statistical Information Service (KOSIS). Results: From 2002 through 2012, CHB incidence rates per 100,000 decreased among indivisuals aged 20-29 years but increased among indivisuals aged 30+ years: CHC incidence rates per 100,000 decreased among 20-39 year-old men but increased in the other groups: LC incidence rates per 100,000 decreased among men aged 20-69 years and women aged 20-59 years but increased among men aged 70+ years and women aged 60+ years: PLC incidence rates per 100,000 decreased among men aged 20-49 years and women aged 20-59 years but increased among men aged 50+ years and women aged 60+ years (all trends showed signifi cant changes). The overall mortalityof PLC decreased in both sexes (the maximum change of a year was in 2011) but did not show signifi cant changes. Conclusions: The incidence rates of CHB, CHC, LC and PLC among the younger decreased and the mortality rates of PLC didn`t decreased signifi cantly. This will help to predict the future prospect of liver diseases in Korea.