한국어판 파킨슨병 삶의 질 축약형 도구의 신뢰도와 타당도 = Reliability and Validity of the Korean Short-form Eight-item Parkinson’s Disease Questionnaire (PDQ-8)

다국어 초록 (Multilingual Abstract)

Objectives: This study aimed to determine the reliability and validity of the Korean Parkinson’s disease questionnaire (PDQ-8) using a standard short-form validation approach. Methods: This cross-sectional psychometric study evaluated 80 outpatients with PD who completed the Korean 39-item Parkinson’s disease questionnaire (PDQ-39) and PDQ-8 tools in random order. The summary index (SI) was calculated for the PDQ-39 (PDQ-39SI) and PDQ-8 (PDQ-8SI). A neurologist performed evaluations using the Hoehn and Yahr (HY) scale, unified Parkinson’s disease rating scale (UPRDS motor), mini-mental state examination (MMSE), Montreal cognitive assessment (MoCA), the clinical dementia rating (CDR), and global deterioration scale (GDS). Results: The PDQ-8SI exhibited appropriate floor effect (2.5%) and ceiling effect (1.3%), with acceptable internal consistency reliability (Cronbach’s α=0.88), item-total correlations (0.48-0.77), and inter-rater reliability (Kappa coefficient=0.53). The PDQ-8 loaded one factor (Eigen value=4.35, 54.51% of the variance) and had broadly similar factor loadings (0.585-0.847). The PDQ-8 had mostly goodness of fit (GFI=0.932, NFI=0.914, TLI=0.973, IFI=0.981, CFI=0.981, and RMSEA=0.056). The PDQ-8SI and PDQ-8 items exhibited good correlations with each other (all p<0.05) and the PDQ-39SI (r=0.91, p<0.001). The PDQ-8SI was correlated with levodopa dose (r=0.28, p=0.028), HY score (r=0.44, p=0.001), UPRDS motor (r=0.45, p=0.007), MMES (r=-0.28, p=0.047), MoCA (r=-0.49, p=0.006), GDS (r=0.33, p=0.025), and CDR (r=0.40, p=0.007), respectively. Conclusions: The PDQ-8 appears to be reliable and valid. It may be useful for quickly and easily evaluating the patient’s perspectives regarding the disease’s impacts, which may guide nursing practice and future research.