급성 천식발작의 응급치료 성적 분석 = An analysis on the treatment outcome of acute asthma attack

다국어 초록 (Multilingual Abstract)

Background and objective .There has been little clinical data on the treatment outcome of pa- tients with acute asthma attack in Korea. We designed a management protocol of acute asthma, and analyzed clinical parameters obtained from this protocol. Method: A total of 32 cases with acute asthma were treated with oxygen, β2 agonist, and methylprednisolone. Ipratropium was added in cases of severe attack. After 90 minutes, intravenous aminophylline was given to the patients with poor response. Result: Beta2 agonist and methylprednisolone were sufficient for symptom control in 17 cases. Ipratropium and aminophylline were added in 6 and 9 cases, respectively. There was no difference in improvement of PEF, heart rate, respiratory rate, PaO2, PaCO2, and SaO2 at 90 minutes and 8 hours between agonist inhalation and subcutaneous group. Serum potassium concentration levels significantly decreased in patients treated with ipratropium or aminophylline (n=15, 4.17+0.45 vs. 3.99±0.35mM/L, p<0.05), compared with patients using only agonist and methylprednisolone (n=17, 3.89+0.30 vs. 4.14+0.46mM/L, p>0.05). Conclusion Subcutaneous agonist may be an alternative to inhalant 0z agonist for the emergency treatment of acute asthma, and we think that a consensus regarding use of aminophylline in the emergency room should be made.