돼지의 分娩誘起에서 Prostaglandin F_(2)α 投與效果 = Effect of Prostaglandin F_(2)α on the Farrowing Induction of sow

국문 초록 (Abstract)

本 實驗은 1988年 9月부터 1990年 5月까지 總 2, 808頭의 姙娠豚을 供試하여 姙娠豚에 Prostaglandin F_(2)α의 投與에 의한 分娩誘起의 實用性을 알기 위하여 投與時期, 投與量, 誘起時間, 誘起時間分布, 生産仔豚에 미치는 影響, 血中 Progesterone 水準의 變化를 檢討하여 다음과 같은 結果를 얻었다.
1. Prostaglandin F_(2)α를 投與한 姙娠母豚 2,798頭中 2, 655頭가 分娩하여 分娩誘起率은 94.89%였다.
2. 交尾後 111일, 112일, 113일째에 Prostaglandin F_(2)α를 10 mg, 15mg을 各各 投與하였을 때 分娩誘起時間은 111일령에서 42.20±34. 61 時間, 43.47±33.08時間, 112일령 에서 34. 53±12.29 시간. 25.31±3.70시 간, 113일령에서 26.04±4.98시간, 24.23±7.43 시간이었고, 113일령 대단위실험군에서 10 mg 投與後 평균 분만유기 시간은 26.42시간으로 投與時期가 分娩豫定日에 가까울수록 分娩이 誘起되기까지의 所要時間이 短縮되었다. (P＜0. 05)
3. Prostaglandin F_(2)α 投與量이 10 mg에서 15 mg으로 增加함에 따라 投與後 分娩이 誘起되기까지의 時間은 短縮되었다.
4. 總産仔豚, 死産仔豚數는 投與時期에 따른 유의성은 인정되지 않았다. 그러나 交尾後 111일령에서 生産되는 仔豚의 活力 및 哺乳能力은 떨어졌다.
5. 血中 Progesterone 水準은 PG F_(2)α 投與前에 17.58±2.84 ng/ml에서 分娩前 12時間사이에서 8.90±3.85ng/ml, 分娩後 12時間사이에서는 5.48±3.26 ng/ml으로 저하되었다.

다국어 초록 (Multilingual Abstract)

This study had been conducted since september, 1988 until may 1990 to examine the utility of prostaglandin F_(2)α on parturition induction in pregnant sows, using 2808 sows on gestation by investigating administration time, the dose of injection, parturitien, induction time, distribution of inuction time, influences of PGF_(2)α on litters and the changes of progesterone concentration in blood.
The results obtained are as follows ;
1. Among 2798 pregnant sows administered with prostaglandin F_(2)α, 2665 sows gave birth to piglets and the rate of parturition was 94.89% .
2. When 10 mg and 15 mg prostaglandin F_(2)α was administered to sow at the day of 111, 112, and 113 after couplation the parturition induction time was 42.20 ± 34.61, 43.47 ± 33.08 in sow 111 day pregnant, 34.53 ± 12.29. 25.31 ± 3.70 in sows 112 days pregnant and 26.04 ± 4.98, 24.23 ± 7.43 in sows 113 days pregnant. As the mean parturition induction times were 26.42 hours in the sows after injection of 10 mg PGF_(2)α on days 113 of gestation the fact that the parturition induction was demontrated(p＜0.05).
3. As the dosage of prostaglandin F_(2)α was increased from 10 mg to 15 mg the interval between administration and parturition induction was shortened.
4. There was no a stastical difference in total litter size and the number of stillbirth in relation to the time of prostaglandin administration but the piglets born from sows being injected on days 111 of gestation showed the reduction of activity and suckling ability.
5. Plasma progesterone concentration in sows before administration, of PGF_(2) was 17.58 t 2.84 ng/mL however with the injection of PGF_(2)α the concentration was decreased to 8.90 ± 3.85 ng/ml for 12 hours before parturition and to 5.48 ± 3.26 ng/ml for 12 hours after farrowing.

목차 (Table of Contents)

• 목차 = ⅰ
• ABSTRACT = 1
• Ⅰ. 緖論 = 4
• Ⅱ. 硏究史 = 6
• Ⅲ. 材料 및 方法 = 9
• Ⅳ. 結果 및 考察 = 12
• 1. 臨床所見 = 12
• 2. 分娩誘起率 = 13
• 3. 分娩誘起 所要時間 = 15
• 4. 分娩成績 = 18
• 5. 血中 Progesterone 氷準의 變化 = 20
• Ⅴ. 摘要 = 23
• 參考文獻 = 25