해양소재를 이용한 마스크팩의 유용성 : 피부재생효과 = Usefullness of Mask Pack Sheets Including Marine Materials: Skin Regeneration Effect

다국어 초록 (Multilingual Abstract)

Minerals from marine materials such as deep ocean water and Dead Sea water have been used since ancient times. We made a mask pack sheet including deep ocean water and salt from the Dead Sea and evaluated the function of the mask pack sheet through animal study.Three full-thickness skin defects were made on the backs of Sprague-Dawley rats.
The wounds were left untreated in group Con, and mask pack sheets including deep ocean water or deep ocean water and Dead Sea water were used as treatment for 20 min on the skin of animals in groups DP and DDP, respectively.
We analyzed the gross, histological and biochemical findings.Groups DDP and DP showed decreases in wound size,as compared to group Con at 7 days after wound infliction. The histological findings revealed that wound healing had progressed further in groups DP and DDP than in group Con, with more rapid collagen deposition and regression of neutrophils.
Also, the expression of vascular endothelial growth factor and transforming growth factor β1 were increased in groups DDP and DP compared with those in group Con at 3 days after wound infliction. Mask sheet packs including deep ocean water and Dead Sea salt affected wound healing by reducing the inflammatory phase and stimulated wound contracture by facilitating the deposition of collagen.

참고문헌 (Reference)

1 정갑택, "해양심층수의 특성과 이용 및 국내외 연구현황" 한국식품영양학회 21 (21): 592-598, 2008

2 장정희, "자외선으로 유도된 섬유아세포 손상에 대한 해양소재 추출물의 항산화 보호효과" 대한화장품학회 36 (36): 79-87, 2010

3 박미순, "아토피성피부염에 대한 미네랄 심층수의 입욕효과" 대한미용학회 7 (7): 181-187, 2011

4 김미영, "미숙사과를 이용한 사과마스크팩의 정기적인 사용이 중년여성의 피부상태 개선에 대한 임상효과 평가" 한국영양학회 43 (43): 453-462, 2010

5 Even-Paz Z, "The Dead Sea and psoriasis. Historical and geographic background" 28 : 1-9, 1989

6 Denda M, "Some magnesium salts and a mixture of magnesiumand calcium salts accelerate skin barrier recovery" 291 : 560-563, 1999

7 Grzesiak JJ, "Shifts in the concentrations of magnesium and calcium in early porcine and rat wound fluids activate the cell migratory response" 95 : 227-233, 1995

8 Diezel W, "Magnesium ion: topical application and inhibition of the croton oil-induced inflammation" 69 : 759-760, 1994

9 Cho HK, "Evaluation of deep sea water on skin barrier function" 13 : 59-65, 2006

10 Kulozik M, "Changes in collagen connective tissue and fibroblasts in aging" 64 : 1003-, 1989

11 Proksch E, "Bathing in a magnesium-rich Dead Sea salt solution improves skin barrier function, enhances skin hydration, and reduces inflammation in atopic dry skin" 44 : 151-157, 2005