수술 후 발견된 갑상선 기능항진증 환자의 전신마취 중 빈맥에 Esmolol보다 Labetalol이 효과가 있었던 경험 - 증례 보고 - = The Effectiveness of Labetalol for Treating Esmolol-resistant Tachycardia in a Patient Who was Under General Anesthesia －A case report－

다국어 초록 (Multilingual Abstract)

Esmolol is a cardioselective beta-blocker with a very rapid onset
of action and a short half-life. Labetalol is a combined alpha- and
beta-adrenoceptor blocking agent. It is a nonselective antagonist
at beta-adrenoceptors and a competitive antagonist of postsynaptic
alpha 1-adrenoceptors. A 51 year old female patient was transferred
to the operating room for performing spinal fusion under
general anesthesia. She had no operation and medication history.
The initial heart rate was 150 beats/min. Despite administering
several bolus injections of esmolol, the heart rate was not decreased
to under 130 beats/min. But the heart rate was decreased to 100
beats/min after the administration of labetalol 5 mg and this rate
was maintained without an additional injection. The vital signs
were stable until the operation was finished and the patient
recovered uneventfully in the recovery room. The postoperative
laboratory findings revealed that she had hyperthyroidism. We
report here on an anesthetic experience of effective labetalol
treatment for esmolol-resistant tachycardia in a patient who was
under general anesthesia.

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