치매와 우울증의 감별을 위한 한국어판 간이정신상태검사의 차별문항 추출 = Measuring Cognition in Elderly People : Mini-Mental State Examination-Korean Version

다국어 초록 (Multilingual Abstract)

Objectives：The Mini-Mental State Examination is arguably the most widely used screening measure for cognitive impairment. The aims of this study are to evaluate the psychometric properties of the Mini-Mental State Examination- Korean Version(MMSE-KC) as a quantitative measure of cognitive ability. Methods：Data were analyzed from a total of 312 participants age 65 or older from cross-sectional community-based study, which were collected about demographic information and individual item responses to MMSE-KC. Item response theory was used to analyze individual items. Results：Comparison of the data with a unidimensional 2-parameter model indicated that the total score obtained by summing across all items yields a reliable(0.78) quantitative estimate of global cognitive ability. All items fit the model and together spanned a range of difficulty(threshold parameter) from -3.86(easier) to 1.15(more difficult) logits, and discrimination(slope parameter) from 0.55 to 8.6 logits. The items about ‘recall of three words’ and ‘attention’ were the most difficult items and have most powerful discrimination parameter. Copying pentagons and time(year) orientation were more difficult than the other items. The patients with dementia showed differential item functioning such items as orientation to place, the last two items of ‘recall of three words’, the last two items of ‘attention’, and ‘three stage command’. Conclusion：The MMSE-KC can provide a reliable and valid quantitative estimate of cognitive ability. More attention should be paid to the difficult items like ‘recall of three words’ and ‘attention’ for the discrimination of dementia from non-dementia people.

목차 (Table of Contents)

• 서론 대상 및 방법 결과 고찰 결론 참고문헌

참고문헌 (Reference)

1 장성만, "한국인의 우울증 진단기준의 특성" 대한신경정신의학회 46 (46): 447-452, 2007

2 조맹제, "한국어판 Composite International Diagnostic Interview(K-CIDI)의 개발" 대한신경정신의학회 41 (41): 2002

3 Folstein MF, "“Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician" 12 : 189-198, 1975

4 Emery VO, "Update on the dementia spectrum of depression" 149 : 305-317, 1992

5 Alexopoulos GS, "The course of geriatric depression with “reversible dementia”: a controlled study" 150 : 1693-1699, 1993

6 Baker FB, "The basics of item response theory. 2nd ed" ERIC Clearinghouse on Assessment and Evaluation 2001

7 Lockwood KA, "Subtypes of cognitive impairment in depressed older adults" 8 : 201-208, 2000

8 Brodaty H, "Prognosis of depression in the elderly. A com-parison with younger patients" 163 : 589-596, 1993

9 Stoudemire A, "Neuropsychological and biomedical assessment of depression-dementia syndromes" 1 : 347-361, 1989

10 이동영, "Mini-Mental State Examination의 한국 노인 정상규준 연구" 대한신경정신의학회 41 (41): 2002

11 Saez-Fonseca JA, "Long-term outcome of depressive pseudodementia in the elderly" 101 : 123-129, 2007

12 Benjamin JS, "Kaplan and Sadocks Comprehensive textbook of psychiatry" LLW 2009

13 Chang CH, "Item response theory and its applications to patient-reported outcomes measurement" 28 : 264-282, 2005

14 Katz IR, "Diagnosis and treatment of depression in patients with Alzheimer’s disease and other dementias" 59 : 38-44, 1998

15 Welsh K, "Detection of abnormal memory decline in mild cases of Alzheimer’s disease using CERAD neuropsychological measures" 48 : 278-281, 1991

16 Reding M, "Depression in patients referred to a dementia clinic. A three-year prospective study" 42 : 894-896, 1985

17 Korczyn AD, "Depression and dementia" 283 : 139-142, 2009

18 Thomas AJ, "Depression and cognition in older adults" 21 : 8-13, 2008

19 Becker JT, "Depressed mood is not a risk factor for incident dementia in a community-based cohort" 17 : 653-663, 2009

20 Benedict KB, "Dementia and depression in the elderly: a framework for addressing difficulties in differential diagnosis" 10 : 513-537, 1990

21 Speedie L, "Confrontation naming deficit in dementia of depression" 23 : 59-63, 1990

22 Reys BN, "Brief cognitive evaluation and diagnosis of dementia, depression, and psychosis in the elderly" 52 : 401-404, 2006

23 Knopman DS, "A verbal memory test with high predictive accuracy for dementia of the Alzheimer type" 46 : 141-145, 1989