경상남도 일부 농촌지역의 간흡충 감염에 대한 역학적 연구 = Epidemiologic Study of Clonorchis Sinensis Infestation in a Rural Area of Kyongsangnam-do, South Korea

다국어 초록 (Multilingual Abstract)

Objectives : To investigate the prevalence of Clonorchis Sinensis infestation and to determine the associated risk factors among a population in a part of the rural area of Gyeongsangnam-do, Korea, which is an area known to have a high mortality from liver cancer and a high infection of C. sinensis. Methods : The study populat ion consisted of those people who have lived in rural areas and who were over 40 years old. This study was performed in 5 areas during the period from 1999 to 200 3. Informed consents were obtained from the 2,381 study participants, and these people were interviewed about their life style habits with using the structured questionnaire that was administered by trained staff members. The subjects underwent blood sampling and their stool specimens were examined by using the Formalin-ether sedimentation technique. Results : Among the study subjects (N=2,381), the positivity for C. sinensis in the stool was 34.4% (95% CI=36.3-42.5); it was 39.4% (95% CI=36.3-42.5) in the males and 30.9% (95% CI=28.5-33.3) in the females . The positivity for C. sinensis was associated with current alcohol drinking (odds ratio=1.8, 95% CI: 1.5-2.1) and raw fish consumption (odds ratio 1.2, 95% CI: 0.9-1.6). Conclusion : The present study confirmed the high prevalence of C. sinensis in the study subjects. It is necessary to establish consistent medical management and education programs for the treatment and prevention of C. sinensis infestation in the rural inhabitants of Korea.

참고문헌 (Reference)

1 "Thedetectability of helminth eggs from feces bycellophane thick smear technique" 20 : 14-20, 1982

2 "The prevalenceof clonrchis sinensis and its related factors atGoksung area in the basin of Sumjin river" 22 (22): 239-252, koreanjruralmed1997

3 "The present status and a proposal ofthe prospective measures for parasitic diseasescontrol in Korea" 1-16, koreajprevnutr1970

4 "The infection status and perceptiontoward intestinal trematodes of an islandinhabitants [dissertation]" Chosun Univ 2000

5 "The current pathobiology andchemotherapy of clonorchiasis" 24 suppl : 1-141, 1986

6 "The Ministry of Health and Welfare KoreaAssociation of Health Promotion Prevenlanceof Intestinal Parasitic Infection in Korea" 1997

7 "Progress inassessment of morbidity due to Clonorchissinensis infection a review of recent literature"

8 "Intestinal parasite and Clonorchis sinensisinfection among the inhabitants in the upperstream of Taechong Dam" 207-214, koreanjparasitol1994

9 "IARC Monographs on theEvaluation of Carcinogenic Risks to HumansVol 61 Schistosomes" 1994

10 "Geographical variation of liver cancermortality in Korea" 35 (35): 420-426, 2001

11 "Epidemiological Studies on Clonorchis sinensisInfection along the Nam-River in Gyeongnamprovince" 167-186, koreanjparasitol1983

12 "Diagnostic usefulness of sonographyaccording to prevalence and intensity ofClonorchis sinensis infection [dissertation]" Seoul National Univ 2004

13 "Current status and the changing pattern ofthe prevalence of clonorchiasis in the inhabitantsin Sanchong-gun" 207-213, koreanjparasitol1993

14 "Clinical feature in clonorchiasis" 27 (27): 64-71, koreanjgastrol1995

15 "Annual Reporton the Cause of Death Statistics" 2002

16 "Anepidemiologic study on clonorchiasis andmetagonimiasis in riverside areas in Korea" 137-150, koreanjparasitol1981

17 "Analysis on the findings ofserum biochemical test in inhabitants infectedwith Clonorchis sinensis" 7 (7): 39-45, 2001

18 "An evaluation on the prevalence of andreinfection after medicine of patients withclonrchis sinensis in an endemic locality" 24 (24): 225-232, koreanjruralmed1999

19 "A seroepidemiologicalsurvey for human clonrchiasis on Soonchanggunnear Sumjin river in Korea" 27 (27): 27-33, koreanjruralmed2002