One hundred and fifty eight patients with carcinoma in situ were reviewed. A discrepancy of histopathologic findings between punch biopsies and subsequent cone specimens was found in 11.5% of cases. Extended hysterectomy was carried out in 96.2% of ca...
One hundred and fifty eight patients with carcinoma in situ were reviewed. A discrepancy of histopathologic findings between punch biopsies and subsequent cone specimens was found in 11.5% of cases. Extended hysterectomy was carried out in 96.2% of cases. The cone-hysterectomy febrile morbidity was found to be 40.3%. The morbidity was increased when the time interval between operations is greater than 72 hours and less than 6 weeks. The 33.8% of patients who had undergone previous cone biopsy had residual carcinoma in the subsequent hysterectomy specimens. Among the 59 patients(37.3%) who were followed postoperatively, one developed an invasive carcinoma of the vagina.