광장 공포증 유무에 따른 공황장애의 임상 양상 차이 = A Comparison of the Clinical Features between Panic Disorder with and without Agoraphobia

다국어 초록 (Multilingual Abstract)

Objectives:This study was performed to investigate the differences of the clinical feature between panic disorder with agoraphobic patients and panic disorder without agoraphobic patients. Methods:Two hundred nine patients meeting the criteria of DSM-IV panic disorder were recruited. One group was panic disorder with agoraphobia(n=78, 42 male(53.8%), mean age $37.6{\pm}9.9$ years), another was panic disorder without agoraphobia(n=131, 81 male(61.8%), mean age $40.5{\pm}10.3$ years). The numbers and frequency of panic symptoms were compared between two groups with t-test, and the logistic regression analysis were used for predicting panic disorder with agoraphobia. Results:The number of panic symptoms during panic attack was significantly higher in the group of panic disorder with agoraphobia than the group of panic disorder without agoraphobia(p<0.05).'Sweating','nausea or abdominal distress','fear of losing control of going crazy','chills or hot flushes'were more frequent in the group of panic disorder with agoraphobia(p<0.05). Among panic symptoms on logistic regression analysis,'sweating',' nausea or abdominal distress','fear of losing control or going crazy'turned out to correlate significantly with risk of development of agoraphobia in panic disorder. Conclusion:These results suggest that the frequency of some symptoms during panic attack may be a predictor of agoraphobia in patients with panic disorder.

참고문헌 (Reference)

1 Cassano GB, "a clinical evaluation on 150 patients with panic disorder/agoraphobia Compr Psychiatry 1989;30" Petracca A 5-12,

2 Goisman RM, "Utilization of behavioral methods in a multicenter anxiety disorder study" 213-218, jclinpsychiatry1993;54

3 Starcevic V, "The phenomenology of panic attack in panic disorder with and without agoraphobia" 36-41, comprpsychiatry1992;34

4 Hale RE, "Textbook of Psychiatry" American Psychiatric Press; 1994 495-497,

5 Briggs AC, "Subtyping of panic disorder by symptomprofile" 201-209, amjpsychiatry1993;163

6 Zoellner LA, "Stability of catastrophic cognitions in panicdisorder." 34 : 399-402, 1996

7 Cox BJ, "Situations and specific coping strategies with clinical and nonclinical panic attacks" 67-69,

8 Arson TA, "Phenomenology of panic attack a descriptive of panic disorder patient's self-reports" 8-13, jclinpsychiatry1988;49

9 Nutt DJ, "Panic Disorder: Clinical diagnosis, management and mechanism." London: Martin Dunitz 28-, 1999

10 Noyes R Jr, "Outcome of panic disorder" 809-818,

11 Bass C, "Hyperventilation and its relationship to anxiety and panic" 274-291, integrpsychiatry1987;5

12 Norton GR, "Factors associated with panic attack in nonclinical subjects" 239-252, behavther1986;17

13 Fleming B, "Discriminating factors in panic disorder with and without agoraphobia" 209-219, janxietydisord1989;3

14 American Psychiatric Association, "Diagnostic and Statistical Manual of Mental Disorders" American Psychiatric Press; 1980 225-239,

15 American Psychiatric Association, "Diagnostic and Statistical Manual of Mental Disorders" American Psychiatric Press; 1994 393-444,

16 American Psychiatric Association, "Diagnostic and Statistical Manual of Mental Disorders" American Psychiatric Press; 1987 235-253,

17 Starcevic V, "Comorbidity in panic disorder"

18 Buller R, "Chronology of panicavoidance age of onset in panic disorder and prediction of treatment response A report from the cross-national collaborative panic study" 163-168,

19 Warshaw MG, "Allsworth J, Keller MB. Predictors of remission in patients with panic with and without agoraphobia : prospectives5-year follow-up data." 185 : 517-519, 1997

20 Maier W, "Agoraphobia in panic disorder an indicator of the severity of panic disorder or a distinct diagnostic entity? Psychiatr Ann 1991;21" 374-381,

21 Craske MG, "A review of the relationship between panic andavoidance" 667-685, clinpsycholrev1988;8